Detail publikačního výsledku

Systematic comparison of advanced network analysis and visualization of lipidomics data

SCHWARZEROVÁ, J.; OLEŠOVÁ, D.; KVASNIČKA, A.; FRIEDECKÝ, D.; VARGA, M.; PROVAZNÍK, V.; WECKWERTH, W.

Originální název

Systematic comparison of advanced network analysis and visualization of lipidomics data

Anglický název

Systematic comparison of advanced network analysis and visualization of lipidomics data

Druh

Stať ve sborníku v databázi WoS či Scopus

Originální abstrakt

Comprehensive analysis of lipids is becoming a forefront of clinical data analysis. Due to significant technical advancements, lipidomics is emerging in clinical diagnostics for improvement and earlier detection of a broad range of diseases. However, in order to understand the biological complexities and interrelationships between the molecules, it is important to have a correct representation of the data and visualizations that enable good interpretability of the lipidomic data. Therefore, the present study systematically compares different visualization methods for lipidomic data, based on different computational relations between the selected lipids and supplemented with known biological information. Networks were reconstructed, and an analysis was performed to objectively compare the visualizations.

Anglický abstrakt

Comprehensive analysis of lipids is becoming a forefront of clinical data analysis. Due to significant technical advancements, lipidomics is emerging in clinical diagnostics for improvement and earlier detection of a broad range of diseases. However, in order to understand the biological complexities and interrelationships between the molecules, it is important to have a correct representation of the data and visualizations that enable good interpretability of the lipidomic data. Therefore, the present study systematically compares different visualization methods for lipidomic data, based on different computational relations between the selected lipids and supplemented with known biological information. Networks were reconstructed, and an analysis was performed to objectively compare the visualizations.

Klíčová slova

Comprehensive Analysis, Networks Analysis, Lipids, Network Visualization

Klíčová slova v angličtině

Comprehensive Analysis, Networks Analysis, Lipids, Network Visualization

Autoři

SCHWARZEROVÁ, J.; OLEŠOVÁ, D.; KVASNIČKA, A.; FRIEDECKÝ, D.; VARGA, M.; PROVAZNÍK, V.; WECKWERTH, W.

Rok RIV

2024

Vydáno

29.06.2023

Nakladatel

SPRINGER INTERNATIONAL PUBLISHING AG

ISBN

978-3-031-34953-9

Kniha

Bioinformatics and Biomedical Engineering

Edice

1

Strany od

378

Strany do

389

Strany počet

12

URL

https://link.springer.com/chapter/10.1007/978-3-031-34953-9_30

BibTex

@inproceedings{BUT184933,
  author="Jana {Schwarzerová} and Dominika {Olešová} and Aleš {Kvasnička} and David {Friedecký} and Margaret {Varga} and Valentýna {Provazník} and Wolfram {Weckwerth}",
  title="Systematic comparison of advanced network analysis and visualization of lipidomics data",
  booktitle="Bioinformatics and Biomedical Engineering",
  year="2023",
  series="1",
  pages="378--389",
  publisher="SPRINGER INTERNATIONAL PUBLISHING AG",
  doi="10.1007/978-3-031-34953-9\{_}30",
  isbn="978-3-031-34953-9",
  url="https://link.springer.com/chapter/10.1007/978-3-031-34953-9_30"
}