Publication result detail

Systematic comparison of advanced network analysis and visualization of lipidomics data

SCHWARZEROVÁ, J.; OLEŠOVÁ, D.; KVASNIČKA, A.; FRIEDECKÝ, D.; VARGA, M.; PROVAZNÍK, V.; WECKWERTH, W.

Original Title

Systematic comparison of advanced network analysis and visualization of lipidomics data

English Title

Systematic comparison of advanced network analysis and visualization of lipidomics data

Type

Paper in proceedings (conference paper)

Original Abstract

Comprehensive analysis of lipids is becoming a forefront of clinical data analysis. Due to significant technical advancements, lipidomics is emerging in clinical diagnostics for improvement and earlier detection of a broad range of diseases. However, in order to understand the biological complexities and interrelationships between the molecules, it is important to have a correct representation of the data and visualizations that enable good interpretability of the lipidomic data. Therefore, the present study systematically compares different visualization methods for lipidomic data, based on different computational relations between the selected lipids and supplemented with known biological information. Networks were reconstructed, and an analysis was performed to objectively compare the visualizations.

English abstract

Comprehensive analysis of lipids is becoming a forefront of clinical data analysis. Due to significant technical advancements, lipidomics is emerging in clinical diagnostics for improvement and earlier detection of a broad range of diseases. However, in order to understand the biological complexities and interrelationships between the molecules, it is important to have a correct representation of the data and visualizations that enable good interpretability of the lipidomic data. Therefore, the present study systematically compares different visualization methods for lipidomic data, based on different computational relations between the selected lipids and supplemented with known biological information. Networks were reconstructed, and an analysis was performed to objectively compare the visualizations.

Keywords

Comprehensive Analysis, Networks Analysis, Lipids, Network Visualization

Key words in English

Comprehensive Analysis, Networks Analysis, Lipids, Network Visualization

Authors

SCHWARZEROVÁ, J.; OLEŠOVÁ, D.; KVASNIČKA, A.; FRIEDECKÝ, D.; VARGA, M.; PROVAZNÍK, V.; WECKWERTH, W.

RIV year

2024

Released

29.06.2023

Publisher

SPRINGER INTERNATIONAL PUBLISHING AG

ISBN

978-3-031-34953-9

Book

Bioinformatics and Biomedical Engineering

Edition

1

Pages from

378

Pages to

389

Pages count

12

URL

https://link.springer.com/chapter/10.1007/978-3-031-34953-9_30

BibTex

@inproceedings{BUT184933,
  author="Jana {Schwarzerová} and Dominika {Olešová} and Aleš {Kvasnička} and David {Friedecký} and Margaret {Varga} and Valentýna {Provazník} and Wolfram {Weckwerth}",
  title="Systematic comparison of advanced network analysis and visualization of lipidomics data",
  booktitle="Bioinformatics and Biomedical Engineering",
  year="2023",
  series="1",
  pages="378--389",
  publisher="SPRINGER INTERNATIONAL PUBLISHING AG",
  doi="10.1007/978-3-031-34953-9\{_}30",
  isbn="978-3-031-34953-9",
  url="https://link.springer.com/chapter/10.1007/978-3-031-34953-9_30"
}