Detail publikačního výsledku

The COG-or: the Improved Functional Annotation of Bacterial Genomes

POLAKOVIČOVÁ, P.; SEDLÁŘ, K.

Originální název

The COG-or: the Improved Functional Annotation of Bacterial Genomes

Anglický název

The COG-or: the Improved Functional Annotation of Bacterial Genomes

Druh

Stať ve sborníku v databázi WoS či Scopus

Originální abstrakt

The study of bacterial organisms is given great emphasis in scientific research. By studying the bacterial genome, scientists can gain knowledge of various infectious diseases. Nowadays, it is even possible to edit genes and thus advancing the field of tailored medicine by treating many genetic diseases. Furthermore, it is becoming the norm to utilize bacteria in the industry for their ability to produce important products such as plastics, or fuels. It is therefore essential to extract the necessary information about its genes and other features. This paper focuses mainly on improving the functional annotation of bacterial genomes, classification of protein-coding sequences into clusters of orthologous groups, and visualization of the final annotated genome. For this task, the python package was developed with several functions for working with the outputs of multiple annotation tools, namely eggNOG-mapper, Operon-mapper, and Batch CD-Search. The package was tested on Clostridium diolis DSM 15410 and Clostridium beijerinckii DSM 791.

Anglický abstrakt

The study of bacterial organisms is given great emphasis in scientific research. By studying the bacterial genome, scientists can gain knowledge of various infectious diseases. Nowadays, it is even possible to edit genes and thus advancing the field of tailored medicine by treating many genetic diseases. Furthermore, it is becoming the norm to utilize bacteria in the industry for their ability to produce important products such as plastics, or fuels. It is therefore essential to extract the necessary information about its genes and other features. This paper focuses mainly on improving the functional annotation of bacterial genomes, classification of protein-coding sequences into clusters of orthologous groups, and visualization of the final annotated genome. For this task, the python package was developed with several functions for working with the outputs of multiple annotation tools, namely eggNOG-mapper, Operon-mapper, and Batch CD-Search. The package was tested on Clostridium diolis DSM 15410 and Clostridium beijerinckii DSM 791.

Klíčová slova

Bacterial genome; Functional annotation; COG; eggNOG-mapper; Operonmapper; Batch CD-Search

Klíčová slova v angličtině

Bacterial genome; Functional annotation; COG; eggNOG-mapper; Operonmapper; Batch CD-Search

Autoři

POLAKOVIČOVÁ, P.; SEDLÁŘ, K.

Rok RIV

2023

Vydáno

06.12.2022

ISBN

978-80-214-6030-0

Kniha

Proceedings II of the 28st Conference STUDENT EEICT 2022: Selected papers

Strany od

84

Strany do

87

Strany počet

4

Plný text v Digitální knihovně

http://hdl.handle.net/

BibTex

@inproceedings{BUT180303,
  author="Petra {Polakovičová} and Karel {Sedlář}",
  title="The COG-or: the Improved Functional Annotation of Bacterial Genomes",
  booktitle="Proceedings II of the 28st Conference STUDENT EEICT 2022: Selected papers",
  year="2022",
  pages="84--87",
  doi="10.13164/eeict.2022.84",
  isbn="978-80-214-6030-0"
}