Detail publikačního výsledku

Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis

LÍZAL, F.; ELCNER, J.; BĚLKA, M.; JEDELSKÝ, J.; HOPKE, P.; ŠTARHA, P.; DRUCKMÜLLEROVÁ, H.; JÍCHA, M.

Originální název

Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis

Anglický název

Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis

Druh

Článek recenzovaný mimo WoS a Scopus

Originální abstrakt

Deposition of fibers in human lungs is known as a health hazard. In-vitro measurements were performed with monodisperse glass fibers in a realistic model of human lungs up to seventh generation of branching to estimate the effect of fiber size and breathing pattern on fiber deposition. Deposited fibers were rinsed from the model segments and gathered on nitrocellulose filters. Phase-contrast microscopy with high resolution camera was used to capture images of filters with fibers. New software was developed for an automated image analysis and local deposition characteristics were calculated afterwards. The whole method proved to be a useful and valuable tool for the evaluation of fiber and particle deposition.

Anglický abstrakt

Deposition of fibers in human lungs is known as a health hazard. In-vitro measurements were performed with monodisperse glass fibers in a realistic model of human lungs up to seventh generation of branching to estimate the effect of fiber size and breathing pattern on fiber deposition. Deposited fibers were rinsed from the model segments and gathered on nitrocellulose filters. Phase-contrast microscopy with high resolution camera was used to capture images of filters with fibers. New software was developed for an automated image analysis and local deposition characteristics were calculated afterwards. The whole method proved to be a useful and valuable tool for the evaluation of fiber and particle deposition.

Klíčová slova

Human Lungs, Deposition, Fibers, Image analysis

Klíčová slova v angličtině

Human Lungs, Deposition, Fibers, Image analysis

Autoři

LÍZAL, F.; ELCNER, J.; BĚLKA, M.; JEDELSKÝ, J.; HOPKE, P.; ŠTARHA, P.; DRUCKMÜLLEROVÁ, H.; JÍCHA, M.

Rok RIV

2014

Vydáno

20.12.2013

Nakladatel

Association for Engineering Mechanics

Místo

Brno

ISSN

1802-1484

Periodikum

Engineering Mechanics

Svazek

20

Číslo

3/4

Stát

Česká republika

Strany od

187

Strany do

194

Strany počet

8

BibTex

@article{BUT96300,
  author="František {Lízal} and Jakub {Elcner} and Miloslav {Bělka} and Jan {Jedelský} and Philip K. {Hopke} and Pavel {Štarha} and Hana {Druckmüllerová} and Miroslav {Jícha}",
  title="Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis",
  journal="Engineering Mechanics",
  year="2013",
  volume="20",
  number="3/4",
  pages="187--194",
  issn="1802-1484"
}