Detail publikačního výsledku

Visualizing Horizontal Gene Transfer Detection in Phylogenetically Divergent Bacteria

SCHWARZEROVÁ, J.; RAJASEKARAN, L.; JUREČKOVÁ, K.; NEJEZCHLEBOVÁ, J.; VARGA, M.; PROVAZNÍK, V.; WECKWERTH, W.; ČEJKOVÁ, D.

Originální název

Visualizing Horizontal Gene Transfer Detection in Phylogenetically Divergent Bacteria

Anglický název

Visualizing Horizontal Gene Transfer Detection in Phylogenetically Divergent Bacteria

Druh

Stať ve sborníku v databázi WoS či Scopus

Originální abstrakt

Horizontal Gene Transfer (HGT) plays an important and indispensable role in the evolution of bacterial genomes, serving as a mechanism that contributes to genetic diversity and enables adaptation across phylogenetically distant taxa. This study introduces an analysis tool implemented as an R package for detecting HGT events in diverse bacterial lineages. The tool combines the integration of a heat-map matrix with phylogenetic analysis visualization techniques to enhance the accuracy and efficiency of HGT event detection. We applied it to a diverse set of bacterial genomes from chicken and pig gut and expanded the results with established methods for HGT detection. The findings demonstrate the capability of our visualization techniques to pinpoint HGT events, offering a valuable tool for researchers to explore the intricate dynamics of bacterial genome evolution.

Anglický abstrakt

Horizontal Gene Transfer (HGT) plays an important and indispensable role in the evolution of bacterial genomes, serving as a mechanism that contributes to genetic diversity and enables adaptation across phylogenetically distant taxa. This study introduces an analysis tool implemented as an R package for detecting HGT events in diverse bacterial lineages. The tool combines the integration of a heat-map matrix with phylogenetic analysis visualization techniques to enhance the accuracy and efficiency of HGT event detection. We applied it to a diverse set of bacterial genomes from chicken and pig gut and expanded the results with established methods for HGT detection. The findings demonstrate the capability of our visualization techniques to pinpoint HGT events, offering a valuable tool for researchers to explore the intricate dynamics of bacterial genome evolution.

Klíčová slova

Mobilome; Bioinformatics Data Visualization; Interspecies Gene Transfer; Advanced Comparative Phylogenetics

Klíčová slova v angličtině

Mobilome; Bioinformatics Data Visualization; Interspecies Gene Transfer; Advanced Comparative Phylogenetics

Autoři

SCHWARZEROVÁ, J.; RAJASEKARAN, L.; JUREČKOVÁ, K.; NEJEZCHLEBOVÁ, J.; VARGA, M.; PROVAZNÍK, V.; WECKWERTH, W.; ČEJKOVÁ, D.

Rok RIV

2025

Vydáno

28.08.2024

Nakladatel

Springer Nature

ISBN

978-3-031-64636-2

Kniha

Lecture Notes in Bioinformatics

Edice

14849

ISSN

1611-3349

Periodikum

Lecture Notes in Computer Science

Svazek

14849

Číslo

II.

Stát

Švýcarská konfederace

Strany od

267

Strany do

277

Strany počet

11

URL

https://link.springer.com/chapter/10.1007/978-3-031-64636-2_20

BibTex

@inproceedings{BUT189428,
  author="Jana {Schwarzerová} and Laxmipriya {Rajasekaran} and Kateřina {Šabatová} and Julie {Nejezchlebová} and Margaret {Varga} and Valentýna {Provazník} and Wolfram {Weckwerth} and Darina {Čejková}",
  title="Visualizing Horizontal Gene Transfer Detection in Phylogenetically Divergent Bacteria",
  booktitle="Lecture Notes in Bioinformatics",
  year="2024",
  series="14849",
  journal="Lecture Notes in Computer Science",
  volume="14849",
  number="II.",
  pages="267--277",
  publisher="Springer Nature",
  doi="10.1007/978-3-031-64636-2\{_}20",
  isbn="978-3-031-64636-2",
  url="https://link.springer.com/chapter/10.1007/978-3-031-64636-2_20"
}