Detail publikačního výsledku

Coherence controlled holographic microscopy – a tool for detection of new biomarkers of head and neck squamous cell carcinoma

VESELÝ, M.; GÁL, B.; ROTTENBERG, J.; PALENIK, M.; HANÁK, J.; ZICHA, D.

Originální název

Coherence controlled holographic microscopy – a tool for detection of new biomarkers of head and neck squamous cell carcinoma

Anglický název

Coherence controlled holographic microscopy – a tool for detection of new biomarkers of head and neck squamous cell carcinoma

Druh

Článek Scopus

Originální abstrakt

Background: Squamous cell carcinoma of the head and neck is characterized by local invasive-ness and metastases to regional lymph nodes. In 60% of cases, these tumours are diagnosed at an advanced stage, and the prognosis is unfavorable. One of the important factors of local, hematogenous or lymphogenic spread of the tumour in the human body is tumour cells‘ migration ability. Advanced microscopic methods provide a new perspective on cell migration. Purpose: This paper presents a coherence controlled holographic microscopy method that pro-vides a non-invasive quantitative evaluation of morphological and dynamic properties of living tumour cells. In connection with this method, new potential bio markers are emerging, the significance of which, however, needs to be verified by correlation with clinical data.

Anglický abstrakt

Background: Squamous cell carcinoma of the head and neck is characterized by local invasive-ness and metastases to regional lymph nodes. In 60% of cases, these tumours are diagnosed at an advanced stage, and the prognosis is unfavorable. One of the important factors of local, hematogenous or lymphogenic spread of the tumour in the human body is tumour cells‘ migration ability. Advanced microscopic methods provide a new perspective on cell migration. Purpose: This paper presents a coherence controlled holographic microscopy method that pro-vides a non-invasive quantitative evaluation of morphological and dynamic properties of living tumour cells. In connection with this method, new potential bio markers are emerging, the significance of which, however, needs to be verified by correlation with clinical data.

Klíčová slova

cell migration; epithelial-mesenchymal transition; head and neck carcinoma, coherence-controlled holographic microscopy; squamous cell carcinoma; tumor markers

Klíčová slova v angličtině

cell migration; epithelial-mesenchymal transition; head and neck carcinoma, coherence-controlled holographic microscopy; squamous cell carcinoma; tumor markers

Autoři

VESELÝ, M.; GÁL, B.; ROTTENBERG, J.; PALENIK, M.; HANÁK, J.; ZICHA, D.

Rok RIV

2023

Vydáno

01.02.2022

ISSN

0862-495X

Periodikum

Klinicka Onkologie

Svazek

35

Číslo

2

Stát

Česká republika

Strany od

128

Strany do

131

Strany počet

4

URL

https://www.linkos.cz/casopis-klinicka-onkologie/2022-04-15-2/koherenci-rizena-holograficka-mikroskopie-nastroj-pro-hledani-novych-bio-markeru/

BibTex

@article{BUT182706,
  author="Miroslav {Veselý} and Břetislav {Gál} and Jan {Rottenberg} and Michal {Palenik} and Jan {Hanák} and Daniel {Zicha}",
  title="Coherence controlled holographic microscopy – a tool for detection of new biomarkers of head and neck squamous cell carcinoma",
  journal="Klinicka Onkologie",
  year="2022",
  volume="35",
  number="2",
  pages="128--131",
  doi="10.48095/ccko2022128",
  issn="0862-495X",
  url="https://www.linkos.cz/casopis-klinicka-onkologie/2022-04-15-2/koherenci-rizena-holograficka-mikroskopie-nastroj-pro-hledani-novych-bio-markeru/"
}