Detail publikačního výsledku

SiO2-decorated Parylene C micropillars designed to probe cellular force

FOHLEROVÁ, Z.; GABLECH, I.; OTÁHAL, A.; FECKO, P.

Originální název

SiO2-decorated Parylene C micropillars designed to probe cellular force

Anglický název

SiO2-decorated Parylene C micropillars designed to probe cellular force

Druh

Abstrakt

Originální abstrakt

Living cells sense and respond to mechanical signals through specific mechanisms that generate traction force. The quantification of cell forces using micropillars can be limited by micropillar stiffness which depends on Young´s modulus of material and aspect ratio of pillars, technological limitation of the fabrication, and microcontact printing of proteins. The work shows “top-down” fabrication of a highly ordered array of SiO2/Parylene C micropillars standing on the Si substrate that can be used as a probe to quantify the force generated from cells.

Anglický abstrakt

Living cells sense and respond to mechanical signals through specific mechanisms that generate traction force. The quantification of cell forces using micropillars can be limited by micropillar stiffness which depends on Young´s modulus of material and aspect ratio of pillars, technological limitation of the fabrication, and microcontact printing of proteins. The work shows “top-down” fabrication of a highly ordered array of SiO2/Parylene C micropillars standing on the Si substrate that can be used as a probe to quantify the force generated from cells.

Klíčová slova

micropillars; parylene-C

Klíčová slova v angličtině

micropillars; parylene-C

Autoři

FOHLEROVÁ, Z.; GABLECH, I.; OTÁHAL, A.; FECKO, P.

Rok RIV

2022

Vydáno

21.10.2021

Nakladatel

SENSORS 2021 conference, Milano, Italy

Strany od

1

Strany do

1

Strany počet

1

BibTex

@misc{BUT174951,
  author="Zdenka {Fohlerová} and Imrich {Gablech} and Alexandr {Otáhal} and Peter {Fecko}",
  title="SiO2-decorated Parylene C micropillars designed to probe cellular force
",
  year="2021",
  pages="1--1",
  publisher="SENSORS 2021 conference, Milano, Italy",
  note="Abstract"
}