Detail publikace

Hysteresis during heating and cooling of hyaluronan solutions in water observed by means of ultrasound velocimetry

JUGL, A. HURČÍKOVÁ, A. PEKAŘ, M.

Originální název

Hysteresis during heating and cooling of hyaluronan solutions in water observed by means of ultrasound velocimetry

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Ultrasound velocity was measured in hyaluronan solutions of various compositions at different temperatures. The velocity dependence on hyaluronan concentration at constant temperature (25 °C) was linear both in water and in 0.15 M NaCl regardless of hyaluronan molecular weight, confirming diluted-solution behavior. During cyclic heating and cooling, hysteresis on the temperature dependence of ultrasound velocity was observed in the range 30–55 °C in aqueous solutions for all molecular weights. In NaCl solutions, the hysteresis was suppressed and, in contrast to solutions in water where the velocity demonstrated a local maximum with temperature, the velocity decreased with increasing temperature. These findings were attributed to slow and hydration-linked hyaluronan conformation transitions during cooling in water, which were suppressed by the presence of salt, which makes hyaluronan's coiled conformation more compact.

Klíčová slova

Hyaluronan; Ultrasound velocimetry; Ultrasonic velocity; Compressibility; Apparent specific compressibility; Hysteresis

Autoři

JUGL, A.; HURČÍKOVÁ, A.; PEKAŘ, M.

Vydáno

15. 12. 2020

ISSN

0141-8130

Periodikum

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Ročník

165

Číslo

Part B

Stát

Nizozemsko

Strany od

2419

Strany do

2424

Strany počet

6

URL

BibTex

@article{BUT165792,
  author="Adam {Jugl} and Andrea {Hurčíková} and Miloslav {Pekař}",
  title="Hysteresis during heating and cooling of hyaluronan solutions in water observed by means of ultrasound velocimetry",
  journal="INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES",
  year="2020",
  volume="165",
  number="Part B",
  pages="2419--2424",
  doi="10.1016/j.ijbiomac.2020.10.165",
  issn="0141-8130",
  url="https://www.sciencedirect.com/science/article/pii/S0141813020348170"
}