Detail publikačního výsledku

Detection of Highly Variable Genome Fragments in Unmapped Reads of Escherichia coli Genomes

NYKRÝNOVÁ, M.; BARTOŇ, V.; BEZDÍČEK, M.; LENGEROVÁ, M.; ŠKUTKOVÁ, H.

Originální název

Detection of Highly Variable Genome Fragments in Unmapped Reads of Escherichia coli Genomes

Anglický název

Detection of Highly Variable Genome Fragments in Unmapped Reads of Escherichia coli Genomes

Druh

Stať ve sborníku v databázi WoS či Scopus

Originální abstrakt

Whole-genome sequencing becomes a powerful tool in the study of closely related bacterial population as a single nucleotides changes can be detected. However, the postprocessing of obtained data still remains problematic. Reference-based assembly of genomes only allows identification of shared parts of genomes. Here, we show a pipeline for de novo assembly of unmapped reads and locating variable regions in it. Identified regions can be used as new markers for bacterial genotyping.

Anglický abstrakt

Whole-genome sequencing becomes a powerful tool in the study of closely related bacterial population as a single nucleotides changes can be detected. However, the postprocessing of obtained data still remains problematic. Reference-based assembly of genomes only allows identification of shared parts of genomes. Here, we show a pipeline for de novo assembly of unmapped reads and locating variable regions in it. Identified regions can be used as new markers for bacterial genotyping.

Klíčová slova

genome assembly; unmapped reads; genotyping

Klíčová slova v angličtině

genome assembly; unmapped reads; genotyping

Autoři

NYKRÝNOVÁ, M.; BARTOŇ, V.; BEZDÍČEK, M.; LENGEROVÁ, M.; ŠKUTKOVÁ, H.

Rok RIV

2021

Vydáno

06.05.2020

ISBN

978-3-030-45384-8

Kniha

Bioinformatics and Biomedical Engineering

ISSN

0302-9743

Periodikum

Lecture Notes in Computer Science

Stát

Spolková republika Německo

Strany od

569

Strany do

578

Strany počet

10

Plný text v Digitální knihovně

http://hdl.handle.net/

BibTex

@inproceedings{BUT163867,
  author="Markéta {Jakubíčková} and Vojtěch {Bartoň} and Matěj {Bezdíček} and Martina {Lengerová} and Helena {Vítková}",
  title="Detection of Highly Variable Genome Fragments in Unmapped Reads of Escherichia coli Genomes",
  booktitle="Bioinformatics and Biomedical Engineering",
  year="2020",
  journal="Lecture Notes in Computer Science",
  pages="569--578",
  doi="10.1007/978-3-030-45385-5\{_}51",
  isbn="978-3-030-45384-8",
  issn="0302-9743"
}