Detail publikačního výsledku

Luminescent Diamond Nanoparticles: Physical, Chemical and Biological Aspects of the Phenomenon (Retracted Article)

KRATOCHVÍLOVÁ, I.; ASHCHEULOV, P.; KOVALENKO, A.; ZÁLIŠ, S.; LEDVINA, M.; MÍČOVÁ, J.

Originální název

Luminescent Diamond Nanoparticles: Physical, Chemical and Biological Aspects of the Phenomenon (Retracted Article)

Anglický název

Luminescent Diamond Nanoparticles: Physical, Chemical and Biological Aspects of the Phenomenon (Retracted Article)

Druh

Článek WoS

Originální abstrakt

Biosensors based on nanodiamonds are able to penetrate through the cell membrane in a targeted manner and probe changes in real-time in the inner cellular space. In this work we performed exclusive theoretical and experimental study of nanodiamond particles adjusted for application in optically-traceable intracellular nanodiamond sensors. Theoretical and experimental study of specific optical properties of high-pressure high-temperature nanodiamonds containing NV- and NV0 centres were performed. The results are supported by theoretical modeling. The final result of this study was detection of luminescence ND in living cells and in vivo application od luminiscence NDs in chicken embryo, showing the detectability of luminescence ND using a standard confocal microscope. On the level of in cells selectivity numerous clusters of ND particles were present within the cytoplasm and at the same time no particles were absent in the nucleus-ND particles can be used as imaging or delivery system for specific cell parts targeting. From our study we can say that biosensors based on nanodiamonds (NDs) are able to penetrate through the cell membrane in a targeted manner and probe changes in the inner cellular space.

Anglický abstrakt

Biosensors based on nanodiamonds are able to penetrate through the cell membrane in a targeted manner and probe changes in real-time in the inner cellular space. In this work we performed exclusive theoretical and experimental study of nanodiamond particles adjusted for application in optically-traceable intracellular nanodiamond sensors. Theoretical and experimental study of specific optical properties of high-pressure high-temperature nanodiamonds containing NV- and NV0 centres were performed. The results are supported by theoretical modeling. The final result of this study was detection of luminescence ND in living cells and in vivo application od luminiscence NDs in chicken embryo, showing the detectability of luminescence ND using a standard confocal microscope. On the level of in cells selectivity numerous clusters of ND particles were present within the cytoplasm and at the same time no particles were absent in the nucleus-ND particles can be used as imaging or delivery system for specific cell parts targeting. From our study we can say that biosensors based on nanodiamonds (NDs) are able to penetrate through the cell membrane in a targeted manner and probe changes in the inner cellular space.

Klíčová slova

Nanodiamonds Luminiscence; NV Centres; In-Cells Imaging; In-Vivo Imaging

Klíčová slova v angličtině

Nanodiamonds Luminiscence; NV Centres; In-Cells Imaging; In-Vivo Imaging

Autoři

KRATOCHVÍLOVÁ, I.; ASHCHEULOV, P.; KOVALENKO, A.; ZÁLIŠ, S.; LEDVINA, M.; MÍČOVÁ, J.

Rok RIV

2020

Vydáno

01.09.2015

Nakladatel

AMER SCIENTIFIC PUBLISHERS

Místo

VALENCIA

ISSN

1533-4899

Periodikum

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Svazek

15

Číslo

2

Stát

Spojené státy americké

Strany od

1000

Strany do

1005

Strany počet

6

URL

Plný text v Digitální knihovně

BibTex

@article{BUT163321,
  author="Irena {Kratochvílová} and Petr {Ashcheulov} and Alexander {Kovalenko} and Stanislav {Záliš} and Miroslav {Ledvina} and Julia {Míčová}",
  title="Luminescent Diamond Nanoparticles: Physical, Chemical and Biological Aspects of the Phenomenon (Retracted Article)",
  journal="JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY",
  year="2015",
  volume="15",
  number="2",
  pages="1000--1005",
  doi="10.1166/jnn.2015.9740",
  issn="1533-4899",
  url="https://www.ingentaconnect.com/content/asp/jnn/2015/00000015/00000002/art00008;jsessionid=j3cw8b1w9cc2.x-ic-live-03"
}