Detail publikačního výsledku

Entropy-Based Detection of Genetic Markers for Bacteria Genotyping

NYKRÝNOVÁ, M.; MADĚRÁNKOVÁ, D.; BARTOŇ, V.; BEZDÍČEK, M.; LENGEROVÁ, M.; ŠKUTKOVÁ, H.

Originální název

Entropy-Based Detection of Genetic Markers for Bacteria Genotyping

Anglický název

Entropy-Based Detection of Genetic Markers for Bacteria Genotyping

Druh

Stať ve sborníku v databázi WoS či Scopus

Originální abstrakt

Genotyping is necessary for the discrimination of bacteria strains. However, methods such as multilocus sequence typing (MLST) or minim typing (mini-MLST) use a combination of several genes. In this paper, we present an augmented method for typing Klebsiella pneumoniae using highly variable fragments of its genome. These fragments were identified based on the entropy of the individual positions. Our method employs both coding and non-coding parts of the genome. These findings may lead to decrease in the number of variable parts used in genotyping and to make laboratory methods faster and cheaper.

Anglický abstrakt

Genotyping is necessary for the discrimination of bacteria strains. However, methods such as multilocus sequence typing (MLST) or minim typing (mini-MLST) use a combination of several genes. In this paper, we present an augmented method for typing Klebsiella pneumoniae using highly variable fragments of its genome. These fragments were identified based on the entropy of the individual positions. Our method employs both coding and non-coding parts of the genome. These findings may lead to decrease in the number of variable parts used in genotyping and to make laboratory methods faster and cheaper.

Klíčová slova

Genotyping;Entropy;Klebsiella pneumoniae;Minim typing

Klíčová slova v angličtině

Genotyping;Entropy;Klebsiella pneumoniae;Minim typing

Autoři

NYKRÝNOVÁ, M.; MADĚRÁNKOVÁ, D.; BARTOŇ, V.; BEZDÍČEK, M.; LENGEROVÁ, M.; ŠKUTKOVÁ, H.

Rok RIV

2020

Vydáno

13.04.2019

ISBN

978-3-030-17934-2

Kniha

Bioinformatics and Biomedical Engineering. IWBBIO 2019.

ISSN

0302-9743

Periodikum

Lecture Notes in Computer Science

Stát

Spolková republika Německo

Strany od

177

Strany do

188

Strany počet

12

BibTex

@inproceedings{BUT156901,
  author="Markéta {Jakubíčková} and Denisa {Maděránková} and Vojtěch {Bartoň} and Matěj {Bezdíček} and Martina {Lengerová} and Helena {Vítková}",
  title="Entropy-Based Detection of Genetic Markers for Bacteria Genotyping",
  booktitle="Bioinformatics and Biomedical Engineering. IWBBIO 2019.",
  year="2019",
  journal="Lecture Notes in Computer Science",
  number="11466",
  pages="177--188",
  doi="10.1007/978-3-030-17935-9\{_}17",
  isbn="978-3-030-17934-2",
  issn="0302-9743"
}