Detail publikace

Mathematical modeling of the IV-administered drug concentration level

RŮŽIČKOVÁ, M. DIBLÍK, J. VÁŽANOVÁ, G.

Originální název

Mathematical modeling of the IV-administered drug concentration level

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

The paper considers models of the IV-administration of a drug with differential equations describing the drug concentration in the body. An explanation is given of the fluctuating and irregular plasma concentration patterns of some drugs observed during intravenous infusion. A new mathematical model is offered of drug intravenous administration with respect to the existence of one or more peaks or undulations of the plasma concentration curve. An illustrative example is considered for certain values of the drug infusion rate and its elimination rate.

Klíčová slova

IV-administration of a drug, differential equation; concentration; elimination rate.

Autoři

RŮŽIČKOVÁ, M.; DIBLÍK, J.; VÁŽANOVÁ, G.

Vydáno

21. 7. 2018

Nakladatel

American Institute of Physics

Místo

AMER INST PHYSICS, 2 HUNTINGTON QUADRANGLE, STE 1NO1, MELVILLE, NY 11747-4501 USA

ISBN

978-0-7354-1690-1

Kniha

INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS (ICNAAM 2017)

ISSN

0094-243X

Periodikum

AIP conference proceedings

Stát

Spojené státy americké

Strany od

430011-1

Strany do

4300011-4

Strany počet

4

URL