Detail publikačního výsledku

Interaction of Graphene Oxide with Proteins and Applications of their Conjugates

ŠIMŠÍKOVÁ, M.; ŠIKOLA, T.

Originální název

Interaction of Graphene Oxide with Proteins and Applications of their Conjugates

Anglický název

Interaction of Graphene Oxide with Proteins and Applications of their Conjugates

Druh

Článek recenzovaný mimo WoS a Scopus

Originální abstrakt

Graphene oxide (GO) has abundant surface oxygen-containing groups such as epoxide, hydroxyl, and carboxylic groups; it can be prepared through the oxidative intercalation and exfoliation of graphite on a mass scale. Owing to the enriched surface functionalities, the GO is water-soluble and chemically versatile. The surface functional groups can also provide plenty of reaction sites for linking nanoparticles, proteins, enzymes, peptides, bacteria, cells, and nucleic acids through covalent and non-covalent binding. GO has been used as a matrix for protein immobilization in different biotechnological applications such as fluorescence- or electrochemical-based sensors, labeling and imaging, therapy, and targeted delivery. This paper reviews the main strategies for the assembly of proteins onto graphene oxide surface and their applications, especially in the biomedical area.

Anglický abstrakt

Graphene oxide (GO) has abundant surface oxygen-containing groups such as epoxide, hydroxyl, and carboxylic groups; it can be prepared through the oxidative intercalation and exfoliation of graphite on a mass scale. Owing to the enriched surface functionalities, the GO is water-soluble and chemically versatile. The surface functional groups can also provide plenty of reaction sites for linking nanoparticles, proteins, enzymes, peptides, bacteria, cells, and nucleic acids through covalent and non-covalent binding. GO has been used as a matrix for protein immobilization in different biotechnological applications such as fluorescence- or electrochemical-based sensors, labeling and imaging, therapy, and targeted delivery. This paper reviews the main strategies for the assembly of proteins onto graphene oxide surface and their applications, especially in the biomedical area.

Klíčová slova

Graphene Oxide; Protein; Interaction; Conjugate

Klíčová slova v angličtině

Graphene Oxide; Protein; Interaction; Conjugate

Autoři

ŠIMŠÍKOVÁ, M.; ŠIKOLA, T.

Rok RIV

2018

Vydáno

08.03.2017

ISSN

2377-4282

Periodikum

Journal of Nanomedicine Research

Svazek

5

Číslo

2

Stát

Spojené státy americké

Strany od

1

Strany do

4

Strany počet

4

BibTex

@article{BUT139931,
  author="Michaela {Šimšíková} and Tomáš {Šikola}",
  title="Interaction of Graphene Oxide with Proteins and Applications of their Conjugates",
  journal="Journal of Nanomedicine Research",
  year="2017",
  volume="5",
  number="2",
  pages="1--4",
  doi="10.15406/jnmr.2017.05.00109",
  issn="2377-4282"
}