Detail aplikovaného výsledku

pqsfinder: an R/Bioconductor package for identification of potential quadruplex forming sequences

HON, J.; LEXA, M.; MARTÍNEK, T.; ZENDULKA, J.

Originální název

pqsfinder: an R/Bioconductor package for identification of potential quadruplex forming sequences

Anglický název

pqsfinder: an R/Bioconductor package for identification of potential quadruplex forming sequences

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Software

Abstrakt

The main functionality of the this package is to detect DNA sequence patterns that are likely to fold into an intramolecular G-quadruplex (G4). Unlike many other approaches, this package is able to detect sequences responsible for G4s folded from imperfect G-runs containing bulges or mismatches and as such is more sensitive than competing algorithms.

Abstrakt aglicky

The main functionality of the this package is to detect DNA sequence patterns that are likely to fold into an intramolecular G-quadruplex (G4). Unlike many other approaches, this package is able to detect sequences responsible for G4s folded from imperfect G-runs containing bulges or mismatches and as such is more sensitive than competing algorithms.

Klíčová slova

G-quadruplex; quadruplex; DNA; R; Bioconductor; pattern matching; searching; annotation

Klíčová slova anglicky

G-quadruplex; quadruplex; DNA; R; Bioconductor; pattern matching; searching; annotation

Umístění

http://bioconductor.org/packages/release/bioc/html/pqsfinder.html

Licenční poplatek

Využití výsledku jiným subjektem je v některých případech možné bez nabytí licence

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