Detail publikačního výsledku

Interaction between Cationic Micelles and Hyaluronan

PILGROVÁ, T.; PEKAŘ, M.

Originální název

Interaction between Cationic Micelles and Hyaluronan

Anglický název

Interaction between Cationic Micelles and Hyaluronan

Druh

Článek Scopus

Originální abstrakt

In this study, results of the research of electrostatic coating of cationic micelle with hyaluronan are reported. The cationic micelle/hyaluronan complexes were studied using turbidimetry and dynamic light scattering method and were evaluated to determine their structure, average size and zeta potential as a function of the amount of the both component in the system. Pilot solubilization experiments were performed to evaluation of stability and solubilization ability of the complexes. Results of turbidimetry revealed that aggregates formation (turbidity increasing) depends especially on hyaluronan concentration while surfactant concentration (above critical micelle concentration) affects interaction insignificantly. Dynamic light scattering experiments indicate that hyaluronan molecular weight has insignificant effect on isoelectric point of the systems. It was found that solubilization ability of the complexes is influenced by molecular weight of hyaluronan.

Anglický abstrakt

In this study, results of the research of electrostatic coating of cationic micelle with hyaluronan are reported. The cationic micelle/hyaluronan complexes were studied using turbidimetry and dynamic light scattering method and were evaluated to determine their structure, average size and zeta potential as a function of the amount of the both component in the system. Pilot solubilization experiments were performed to evaluation of stability and solubilization ability of the complexes. Results of turbidimetry revealed that aggregates formation (turbidity increasing) depends especially on hyaluronan concentration while surfactant concentration (above critical micelle concentration) affects interaction insignificantly. Dynamic light scattering experiments indicate that hyaluronan molecular weight has insignificant effect on isoelectric point of the systems. It was found that solubilization ability of the complexes is influenced by molecular weight of hyaluronan.

Klíčová slova

micelle, hyaluronan, turbidimetry, dynamic light scattering, interactions

Klíčová slova v angličtině

micelle, hyaluronan, turbidimetry, dynamic light scattering, interactions

Autoři

PILGROVÁ, T.; PEKAŘ, M.

Rok RIV

2017

Vydáno

04.12.2015

Nakladatel

Trans Tech Publications Ltd

Místo

Schwitzerland

ISSN

0255-5476

Periodikum

Materials Science Forum

Číslo

851

Stát

Švýcarská konfederace

Strany od

26

Strany do

31

Strany počet

6

URL

http://www.scientific.net/MSF.851.26

BibTex

@article{BUT127384,
  author="Tereza {Pilgrová} and Miloslav {Pekař}",
  title="Interaction between Cationic Micelles and Hyaluronan",
  journal="Materials Science Forum",
  year="2015",
  number="851",
  pages="26--31",
  doi="10.4028/www.scientific.net/MSF.851.26",
  issn="0255-5476",
  url="http://www.scientific.net/MSF.851.26"
}