Detail publikačního výsledku

Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery

SALAMON, D.; TEIXEIRA, S.; DUTCZAK, S.; STAMATIALIS, D.

Originální název

Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery

Anglický název

Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery

Druh

Článek WoS

Originální abstrakt

Nowadays, diffusion through scaffold and tissue usually limits transport, and forms potentially hypoxic regions. Several methods are used for preparation of 3D hydroxyapatite scaffolds, however, production of a scaffold including porous hollow fibers for nutrition delivery is difficult and expensive. In this study, we describe an easy and inexpensive method to create 3D hydroxyapatite structure containing porous hollow fibers via microtemplating. The fibers which are assembled into 3D scaffold and sintered, contain asymmetric membrane walls with flux suitable for nutrient delivery. These hollow fibers have good mesenchymal stem cell adhesion showing that the presented method has no negative influence on cell cytocompatibility. The proposed straightforward method for building 3D structures containing porous hollow fibers for nutritions can be suitable for in vitro bioreactors studies as well as for production tissue engineered or in vivo prepared bone grafts.

Anglický abstrakt

Nowadays, diffusion through scaffold and tissue usually limits transport, and forms potentially hypoxic regions. Several methods are used for preparation of 3D hydroxyapatite scaffolds, however, production of a scaffold including porous hollow fibers for nutrition delivery is difficult and expensive. In this study, we describe an easy and inexpensive method to create 3D hydroxyapatite structure containing porous hollow fibers via microtemplating. The fibers which are assembled into 3D scaffold and sintered, contain asymmetric membrane walls with flux suitable for nutrient delivery. These hollow fibers have good mesenchymal stem cell adhesion showing that the presented method has no negative influence on cell cytocompatibility. The proposed straightforward method for building 3D structures containing porous hollow fibers for nutritions can be suitable for in vitro bioreactors studies as well as for production tissue engineered or in vivo prepared bone grafts.

Klíčová slova

Sintering; Membrane; Hydroxyapatite; Microtemplating; Cell adhesion

Klíčová slova v angličtině

Sintering; Membrane; Hydroxyapatite; Microtemplating; Cell adhesion

Autoři

SALAMON, D.; TEIXEIRA, S.; DUTCZAK, S.; STAMATIALIS, D.

Rok RIV

2015

Vydáno

30.06.2014

ISSN

0272-8842

Periodikum

Ceramics International

Svazek

40

Číslo

9

Stát

Spojené království Velké Británie a Severního Irska

Strany od

14793

Strany do

14799

Strany počet

6

BibTex

@article{BUT110617,
  author="David {Salamon} and Sandra {Teixeira} and Szymon M. {Dutczak} and Dimitrios F. {Stamatialis}",
  title="Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery",
  journal="Ceramics International",
  year="2014",
  volume="40",
  number="9",
  pages="14793--14799",
  doi="10.1016/j.ceramint.2014.06.071",
  issn="0272-8842"
}