Detail publikačního výsledku

Serum metallothioneins in childhood tumours – A potential prognostic marker

KRUSEOVÁ, J.; HYNEK, D.; ADAM, V.; KIZEK, R.; PRŮŠA, R.; HRABĚTA, J.; ECKSCHLAGER, T.

Originální název

Serum metallothioneins in childhood tumours – A potential prognostic marker

Anglický název

Serum metallothioneins in childhood tumours – A potential prognostic marker

Druh

Článek WoS

Originální abstrakt

Metallothioneins (MT) are low molecular weight, cysteine-rich proteins maintaining metal ions homeostasis. They play a role in carcinogenesis and may also cause chemoresistance. The aim of the study was to explore the importance of MT serum levels in children suffering from malignant tumours. This prospective study involves examination of 865 samples from 172 patients with malignant tumours treated from 2008 to 2011 at University Hospital Motol. MT serum levels were determined using differential pulse voltammetry–Brdicka reaction

Anglický abstrakt

Metallothioneins (MT) are low molecular weight, cysteine-rich proteins maintaining metal ions homeostasis. They play a role in carcinogenesis and may also cause chemoresistance. The aim of the study was to explore the importance of MT serum levels in children suffering from malignant tumours. This prospective study involves examination of 865 samples from 172 patients with malignant tumours treated from 2008 to 2011 at University Hospital Motol. MT serum levels were determined using differential pulse voltammetry–Brdicka reaction

Klíčová slova

metallothionein, prognostic marker, cysteine, chemoresistance

Klíčová slova v angličtině

metallothionein, prognostic marker, cysteine, chemoresistance

Autoři

KRUSEOVÁ, J.; HYNEK, D.; ADAM, V.; KIZEK, R.; PRŮŠA, R.; HRABĚTA, J.; ECKSCHLAGER, T.

Rok RIV

2014

Vydáno

06.06.2013

Nakladatel

MDPI

ISSN

1422-0067

Periodikum

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Svazek

14

Číslo

6

Stát

Švýcarská konfederace

Strany od

12170

Strany do

12185

Strany počet

16

URL

http://www.mdpi.com/1422-0067/14/6/12170

Plný text v Digitální knihovně

http://hdl.handle.net/11012/70082

BibTex

@article{BUT101188,
  author="Jarmila {Kruseová} and David {Hynek} and Vojtěch {Adam} and René {Kizek} and Richard {Průša} and Jan {Hraběta} and Tomáš {Eckschlager}",
  title="Serum metallothioneins in childhood tumours – A potential prognostic marker",
  journal="INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES",
  year="2013",
  volume="14",
  number="6",
  pages="12170--12185",
  doi="10.3390/ijms140612170",
  issn="1661-6596",
  url="http://www.mdpi.com/1422-0067/14/6/12170"
}

Dokumenty

ijms-14-12170