Detail publikačního výsledku

DNA-doxorubicin interactions revealed by electrochemistry

MASAŘIK,M.; KYNCLOVA,H.; HÚSKA,D.; HUBÁLEK,J.; ADAM,V., BABULA,P.; ECKSCHLAGER,T.; STIBOROVÁ,M., KIZEK,R.

Originální název

DNA-doxorubicin interactions revealed by electrochemistry

Anglický název

DNA-doxorubicin interactions revealed by electrochemistry

Druh

Abstrakt

Originální abstrakt

Anthracyclines including doxorubicin are commonly used in the treatment of a number of diverse malignant tumours - acute leukaemia, non-Hodgkin and Hodgkin lymphoma and several solid tumours including neuroblastoma. The aim of this study was to compare effects of doxorubicin on sensitive and resistant cells by using electrochemical and mathematical methods. We compared differences between signals of DNA isolated from sensitive and resistant tumour cells by statistical models.

Anglický abstrakt

Anthracyclines including doxorubicin are commonly used in the treatment of a number of diverse malignant tumours - acute leukaemia, non-Hodgkin and Hodgkin lymphoma and several solid tumours including neuroblastoma. The aim of this study was to compare effects of doxorubicin on sensitive and resistant cells by using electrochemical and mathematical methods. We compared differences between signals of DNA isolated from sensitive and resistant tumour cells by statistical models.

Klíčová slova

doxorubicin, Anthracyclines

Klíčová slova v angličtině

doxorubicin, Anthracyclines

Autoři

MASAŘIK,M.; KYNCLOVA,H.; HÚSKA,D.; HUBÁLEK,J.; ADAM,V., BABULA,P.; ECKSCHLAGER,T.; STIBOROVÁ,M., KIZEK,R.

Rok RIV

2013

Vydáno

01.01.2010

Nakladatel

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

ISSN

1107-3756

Periodikum

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Svazek

26

Číslo

1

Stát

Spojené státy americké

Strany od

S46

Strany do

S46

Strany počet

1