Detail publikačního výsledku

Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments

BURGETOVÁ, I.; ZENDULKA, J.; LEXA, M.

Originální název

Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments

Anglický název

Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments

Druh

Stať ve sborníku v databázi WoS či Scopus

Originální abstrakt

In this paper, we propose a novel method for clustering of protein substructures that we developed to study the relationships between protein sequences and their corresponding structures. We show the results of the comparison to other commonly used methods for clustering of protein structures. Finally, we outline a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.

Anglický abstrakt

In this paper, we propose a novel method for clustering of protein substructures that we developed to study the relationships between protein sequences and their corresponding structures. We show the results of the comparison to other commonly used methods for clustering of protein structures. Finally, we outline a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.

Klíčová slova

Clustering, density-based clustering, clustering of protein substructures, sequence-structure relationships in proteins

Klíčová slova v angličtině

Clustering, density-based clustering, clustering of protein substructures, sequence-structure relationships in proteins

Autoři

BURGETOVÁ, I.; ZENDULKA, J.; LEXA, M.

Rok RIV

2011

Vydáno

01.09.2010

Nakladatel

Springer Verlag

Místo

Heidelberg

ISBN

978-3-642-15019-7

Kniha

Information Technology in Bio- and Medical Informatics, ITBAM 2010

Edice

Lecture Notes in Computer Science

Svazek

6266

Strany od

94

Strany do

101

Strany počet

8

BibTex

@inproceedings{BUT35834,
  author="Ivana {Burgetová} and Jaroslav {Zendulka} and Matej {Lexa}",
  title="Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments",
  booktitle="Information Technology in Bio- and Medical Informatics, ITBAM 2010",
  year="2010",
  series="Lecture Notes in Computer Science",
  volume="6266",
  pages="94--101",
  publisher="Springer Verlag",
  address="Heidelberg",
  doi="10.1007/978-3-642-15020-3\{_}9",
  isbn="978-3-642-15019-7"
}