Detail publikačního výsledku

Similarity analysis of primary and secondary structures of metallothioneins

ŠKUTKOVÁ, H.; PROVAZNÍK, I.; KIZEK, R.

Originální název

Similarity analysis of primary and secondary structures of metallothioneins

Anglický název

Similarity analysis of primary and secondary structures of metallothioneins

Druh

Stať ve sborníku v databázi WoS či Scopus

Originální abstrakt

Metallothioneins (MTs) are small cysteine-rich proteins that are involved in many diverse biological processes, which are interesting especially due to their influence on therapy of cancer. The primary structures of MTs from different organisms are various despite they have the same purpose - a transport of metal ions in organisms. Every single mutation in amino acid sequences can have a drastic effect to secondary structures thereby on MTs function. This study presents dependence of diversity of primary and secondary structures on function of MTs.

Anglický abstrakt

Metallothioneins (MTs) are small cysteine-rich proteins that are involved in many diverse biological processes, which are interesting especially due to their influence on therapy of cancer. The primary structures of MTs from different organisms are various despite they have the same purpose - a transport of metal ions in organisms. Every single mutation in amino acid sequences can have a drastic effect to secondary structures thereby on MTs function. This study presents dependence of diversity of primary and secondary structures on function of MTs.

Klíčová slova

phylogentic tree, neigbour-joining, BIONJ, Jukes-Cantor, metallothionein, isoforms, phylogenetic network, NeighborNet, metal ions

Klíčová slova v angličtině

phylogentic tree, neigbour-joining, BIONJ, Jukes-Cantor, metallothionein, isoforms, phylogenetic network, NeighborNet, metal ions

Autoři

ŠKUTKOVÁ, H.; PROVAZNÍK, I.; KIZEK, R.

Rok RIV

2011

Vydáno

02.11.2010

Nakladatel

IEEE

Místo

Corfu

ISBN

978-1-4244-6560-6

Kniha

The 10th IEEE International Conference on Information Technology and Applications in Biomedicine: Emerging Technologies for Patient Specific Healthcare

Strany od

1

Strany do

4

Strany počet

4

BibTex

@inproceedings{BUT34568,
  author="Helena {Vítková} and Valentýna {Provazník} and René {Kizek}",
  title="Similarity analysis of primary and secondary structures of metallothioneins",
  booktitle="The 10th IEEE International Conference on Information Technology and Applications in Biomedicine: Emerging Technologies for Patient Specific Healthcare",
  year="2010",
  number="10",
  pages="1--4",
  publisher="IEEE",
  address="Corfu",
  isbn="978-1-4244-6560-6"
}