Detail publikačního výsledku

3D PRINTABLE POLY(ETHYLENE GLYCOL) BASED HYDROGELS AS AUSPICIOUS MATERIAL FOR DRUG DELIVERY SYSTEMS

SOKOLÍNSKÝ, J.; KREUZEROVÁ, M.; MICHLOVSKÁ, L.; SEDLÁČEK, P.

Originální název

3D PRINTABLE POLY(ETHYLENE GLYCOL) BASED HYDROGELS AS AUSPICIOUS MATERIAL FOR DRUG DELIVERY SYSTEMS

Anglický název

3D PRINTABLE POLY(ETHYLENE GLYCOL) BASED HYDROGELS AS AUSPICIOUS MATERIAL FOR DRUG DELIVERY SYSTEMS

Druh

Abstrakt

Originální abstrakt

Hydrogels are three-dimensional polymer networks with high water content and flexibility. Their properties can be tailored by adjusting polymer concentration, solvent, or additives. Due to their softness, elasticity, biocompatibility, and responsiveness to external stimuli, they are considered smart materials with broad application potential. They are classified as physical or chemical. Physical hydrogels are formed through non-covalent interactions and are generally less stable, often undergoing gel–sol transitions with temperature changes. Chemical hydrogels are created by covalent cross-linking, forming stable three-dimensional networks. Poly(ethylene glycol) (PEG), composed of repeating ethylene glycol units [–(CH₂CH₂O)ₙ–], is widely used for chemically cross-linked hydrogels because of its flexibility, hydrophilicity, and biocompatibility. PEG-based hydrogels are commonly prepared by photopolymerization of PEG diacrylate (PEG-DA) using UV or visible light initiators, enabling rapid and spatially controlled curing. This makes PEG-DA particularly suitable for 3D printing of customizable hydrogel carrier systems.

Anglický abstrakt

Hydrogels are three-dimensional polymer networks with high water content and flexibility. Their properties can be tailored by adjusting polymer concentration, solvent, or additives. Due to their softness, elasticity, biocompatibility, and responsiveness to external stimuli, they are considered smart materials with broad application potential. They are classified as physical or chemical. Physical hydrogels are formed through non-covalent interactions and are generally less stable, often undergoing gel–sol transitions with temperature changes. Chemical hydrogels are created by covalent cross-linking, forming stable three-dimensional networks. Poly(ethylene glycol) (PEG), composed of repeating ethylene glycol units [–(CH₂CH₂O)ₙ–], is widely used for chemically cross-linked hydrogels because of its flexibility, hydrophilicity, and biocompatibility. PEG-based hydrogels are commonly prepared by photopolymerization of PEG diacrylate (PEG-DA) using UV or visible light initiators, enabling rapid and spatially controlled curing. This makes PEG-DA particularly suitable for 3D printing of customizable hydrogel carrier systems.

Klíčová slova

poly(ethylene glycol), 3D printing, drug release, diffusion, tuneable properties

Klíčová slova v angličtině

poly(ethylene glycol), 3D printing, drug release, diffusion, tuneable properties

Autoři

SOKOLÍNSKÝ, J.; KREUZEROVÁ, M.; MICHLOVSKÁ, L.; SEDLÁČEK, P.

Vydáno

11.12.2025

Nakladatel

Vysoké učení technické v Brně

Místo

Brno

ISBN

978-80-214-6388-2

Kniha

sborník abstraktů-Chemistry is life 2025

Strany počet

91

URL

https://www.fch.vut.cz/vav/konference/sok/vystupy

BibTex

@misc{BUT201190,
  author="Jan {Sokolínský} and Monika {Kreuzerová} and Lenka {Michlovská} and Petr {Sedláček}",
  title="3D PRINTABLE POLY(ETHYLENE GLYCOL) BASED HYDROGELS AS AUSPICIOUS MATERIAL FOR DRUG DELIVERY SYSTEMS",
  booktitle="sborník abstraktů-Chemistry is life 2025",
  year="2025",
  pages="91",
  publisher="Vysoké učení technické v Brně",
  address="Brno",
  isbn="978-80-214-6388-2",
  url="https://www.fch.vut.cz/vav/konference/sok/vystupy",
  note="Abstract"
}