Applications of electrochemical sensors for determining acetaminophen and ibuprofen in water samples: A review

Applications of electrochemical sensors for determining acetaminophen and ibuprofen in water samples: A review

Článek WoS

Acetaminophen (APAP) and ibuprofen (IBU) are among the most widely used analgesics for the treatment of fever, pain, and inflammation. While they play a crucial role in improving health conditions, their extensive use, often without the need for a medical prescription, has led to growing environmental concerns. The review highlights recent advances from 2019 to 2024 in the development of electrochemical sensors for the detection of APAP and IBU in various water matrices, including surface water, groundwater, wastewater, tap water and bottled water. In addition, it provides an overview of their metabolic pathways and electrochemical oxidation mechanisms. Materials used for electrode modification, such as carbon-based nanomaterials, metallic nano-particles, metal-organic frameworks (MOFs), and synthetic polymers, have led to substantial improvements in sensor sensitivity and selectivity. The electrochemical detection of APAP and IBU offers a promising strategy for accurate and reliable analysis, with significant implications for environmental monitoring and public health. This review presents a comprehensive evaluation of the analytical performance of various sensors, comparing key analytical parameters such as limit of detection (LOD), linearity range, and relative standard deviations (RSD). The review also outlines key future research directions, including the use of biosensors and automation of detection systems to increase to increase their applicability directly in water environments.

Acetaminophen (APAP) and ibuprofen (IBU) are among the most widely used analgesics for the treatment of fever, pain, and inflammation. While they play a crucial role in improving health conditions, their extensive use, often without the need for a medical prescription, has led to growing environmental concerns. The review highlights recent advances from 2019 to 2024 in the development of electrochemical sensors for the detection of APAP and IBU in various water matrices, including surface water, groundwater, wastewater, tap water and bottled water. In addition, it provides an overview of their metabolic pathways and electrochemical oxidation mechanisms. Materials used for electrode modification, such as carbon-based nanomaterials, metallic nano-particles, metal-organic frameworks (MOFs), and synthetic polymers, have led to substantial improvements in sensor sensitivity and selectivity. The electrochemical detection of APAP and IBU offers a promising strategy for accurate and reliable analysis, with significant implications for environmental monitoring and public health. This review presents a comprehensive evaluation of the analytical performance of various sensors, comparing key analytical parameters such as limit of detection (LOD), linearity range, and relative standard deviations (RSD). The review also outlines key future research directions, including the use of biosensors and automation of detection systems to increase to increase their applicability directly in water environments.

Electroanalytical techniques, Electrode surface modification, Environmental monitoring, Paracetamol, Nonsteroidal anti-inflammatory drugs (NSAIDs)

Electroanalytical techniques, Electrode surface modification, Environmental monitoring, Paracetamol, Nonsteroidal anti-inflammatory drugs (NSAIDs)

NDREKA, X.; KUDR, J.; MIGLIACCIO, L.; ZÍTKA, O.

01.11.2025

ELECTROCHIMICA ACTA

539

Spojené království Velké Británie a Severního Irska

17

https://www.sciencedirect.com/science/article/pii/S0013468625014094