Topological entropy calculations on the molecular sequences

Topological entropy calculations on the molecular sequences

Článek Scopus

We worked on the energy contained in the molecules arranged in genetic molecular sequence. The binding energy of the genetic alphabet, i.e., A, C, G, T have been taken from experimental data and they are used in the calculation of the entropy along the sequence. This is termed as topological entropy on the molecular sequence. The topological entropy of various species is used for principal component analysis, which is a tool to reduce the multidimensional data to less dimension for data visualization. Further the output of the analysis is used for the determination of dissimilarity between the sequences. The technique is verified using HEV molecular sequences.

We worked on the energy contained in the molecules arranged in genetic molecular sequence. The binding energy of the genetic alphabet, i.e., A, C, G, T have been taken from experimental data and they are used in the calculation of the entropy along the sequence. This is termed as topological entropy on the molecular sequence. The topological entropy of various species is used for principal component analysis, which is a tool to reduce the multidimensional data to less dimension for data visualization. Further the output of the analysis is used for the determination of dissimilarity between the sequences. The technique is verified using HEV molecular sequences.

topological entropy, HEV molecular sequences, calculations

topological entropy, HEV molecular sequences, calculations

SARKAR, A.; SARKAR, B.; ZMEŠKAL, O.

2024

12.09.2023

AIP publishing

0094-243X

AIP conference proceedings

2894

020017

Spojené státy americké

020017-1

020017-11

11

https://pubs.aip.org/aip/acp/article/2894/1/020017/2910829/Topological-entropy-calculations-on-the-molecular