Detail publikačního výsledku

Swarming Magnetic Photoactive Microrobots for Dental Implant Biofilm Eradication

MAYORGA-MARTINEZ, C.; ZELENKA, J.; KLÍMA, K.; MAYORGA BURREZO, P.; HOANG, L.; RUML, T.; PUMERA, M.

Originální název

Swarming Magnetic Photoactive Microrobots for Dental Implant Biofilm Eradication

Anglický název

Swarming Magnetic Photoactive Microrobots for Dental Implant Biofilm Eradication

Druh

Článek WoS

Originální abstrakt

Titanium dental implants are a multibillion dollar market in the United States alone. The growth of a bacterial biofilm on a dental implant can cause gingivitis, implant loss, and expensive subsequent care. Herein, we demonstrate the efficient eradication of dental biofilm on titanium dental implants via swarming magnetic microrobots based on ferromagnetic (Fe3O4) and photoactive (BiVO4) materials through polyethylenimine micelles. The ferromagnetic component serves as a propulsion force using a transversal rotating magnetic field while BiVO4 is the photoactive generator of reactive oxygen species to eradicate the biofilm colonies. Such photoactive magnetically powered, precisely navigated microrobots are able to destroy biofilm colonies on titanium implants, demonstrating their use in precision medicine.

Anglický abstrakt

Titanium dental implants are a multibillion dollar market in the United States alone. The growth of a bacterial biofilm on a dental implant can cause gingivitis, implant loss, and expensive subsequent care. Herein, we demonstrate the efficient eradication of dental biofilm on titanium dental implants via swarming magnetic microrobots based on ferromagnetic (Fe3O4) and photoactive (BiVO4) materials through polyethylenimine micelles. The ferromagnetic component serves as a propulsion force using a transversal rotating magnetic field while BiVO4 is the photoactive generator of reactive oxygen species to eradicate the biofilm colonies. Such photoactive magnetically powered, precisely navigated microrobots are able to destroy biofilm colonies on titanium implants, demonstrating their use in precision medicine.

Klíčová slova

bacterial biofilm; photoactive material; ferromagnetic material; polymer micelles; micromotors

Klíčová slova v angličtině

bacterial biofilm; photoactive material; ferromagnetic material; polymer micelles; micromotors

Autoři

MAYORGA-MARTINEZ, C.; ZELENKA, J.; KLÍMA, K.; MAYORGA BURREZO, P.; HOANG, L.; RUML, T.; PUMERA, M.

Rok RIV

2023

Vydáno

28.06.2022

Nakladatel

AMER CHEMICAL SOC

Místo

WASHINGTON

ISSN

1936-086X

Periodikum

ACS Nano

Svazek

16

Číslo

6

Stát

Spojené státy americké

Strany od

8694

Strany do

8703

Strany počet

10

URL

https://pubs.acs.org/doi/10.1021/acsnano.2c02516

Plný text v Digitální knihovně

http://hdl.handle.net/

BibTex

@article{BUT178683,
  author="Carmen C. {Mayorga-Martinez} and Jaroslav {Zelenka} and Karel {Klíma} and Paula {Mayorga Burrezo} and Lan {Hoang} and Tomáš {Ruml} and Martin {Pumera}",
  title="Swarming Magnetic Photoactive Microrobots for Dental Implant Biofilm Eradication",
  journal="ACS Nano",
  year="2022",
  volume="16",
  number="6",
  pages="8694--8703",
  doi="10.1021/acsnano.2c02516",
  issn="1936-0851",
  url="https://pubs.acs.org/doi/10.1021/acsnano.2c02516"
}