Detail publikačního výsledku

RESORBABLE POLYMER-PHOSPHATE BONE CEMENT: THE EFFECT OF MICROFIBERS MODIFICATION

DZUROV, M.; MONTUFAR JIMENEZ, E.; VALOVÁ, K.; LYSÁKOVÁ, K.; ČELKO, L.; KAISER, J.; RAMPICHOVÁ, M.; VOJTOVÁ, L.; BUZGO, M.

Originální název

RESORBABLE POLYMER-PHOSPHATE BONE CEMENT: THE EFFECT OF MICROFIBERS MODIFICATION

Anglický název

RESORBABLE POLYMER-PHOSPHATE BONE CEMENT: THE EFFECT OF MICROFIBERS MODIFICATION

Druh

Abstrakt

Originální abstrakt

In this work, hydrophobic and amphiphilic bioresorbable electrospun microfibers were used to reinforce the calcium phosphate bone cement. Addition of these fibers increased mechanical properties in terms of compressive strength. The fiber amount was optimized in terms of final cement injectability. X-ray diffraction analysis proved full transformation of calcium phosphate to calcium defficient hydroxyapatite after fiber addition. Scanning electron microscopy was used to study microstructure and failure modes at crack interfaces. For better resorption rates, microporositi was modulated. Experiments proved utilization of microfibers as bone cement reinforcement and when loaded with bioactive molecules, they can be used in cements as drug delivery systems.

Anglický abstrakt

In this work, hydrophobic and amphiphilic bioresorbable electrospun microfibers were used to reinforce the calcium phosphate bone cement. Addition of these fibers increased mechanical properties in terms of compressive strength. The fiber amount was optimized in terms of final cement injectability. X-ray diffraction analysis proved full transformation of calcium phosphate to calcium defficient hydroxyapatite after fiber addition. Scanning electron microscopy was used to study microstructure and failure modes at crack interfaces. For better resorption rates, microporositi was modulated. Experiments proved utilization of microfibers as bone cement reinforcement and when loaded with bioactive molecules, they can be used in cements as drug delivery systems.

Klíčová slova

calcium phosphate bone cement, polymer-phosphate bone cement, microfiber reinforcement, mechanical characterization, injectability, electron microscopy, powder X-ray diffraction

Klíčová slova v angličtině

calcium phosphate bone cement, polymer-phosphate bone cement, microfiber reinforcement, mechanical characterization, injectability, electron microscopy, powder X-ray diffraction

Autoři

DZUROV, M.; MONTUFAR JIMENEZ, E.; VALOVÁ, K.; LYSÁKOVÁ, K.; ČELKO, L.; KAISER, J.; RAMPICHOVÁ, M.; VOJTOVÁ, L.; BUZGO, M.

Rok RIV

2022

Vydáno

14.05.2020

Nakladatel

Chemické listy

Místo

Praha

ISSN

2336-7210

Periodikum

Czech Chemical Society Symposium Series

Svazek

18

Číslo

4

Stát

Česká republika

Strany od

255

Strany do

255

Strany počet

1

URL

http://www.insterdisciplinarymeeting.cz/shell/sbornik-2020.pdf

BibTex

@misc{BUT172302,
  author="Matej {Dzurov} and Edgar Benjamin {Montufar Jiménez} and Kristýna {Hlináková} and Klára {Tušlová} and Ladislav {Čelko} and Jozef {Kaiser} and Michaela {Rampichová} and Lucy {Vojtová} and Matěj {Buzgo}",
  title="RESORBABLE POLYMER-PHOSPHATE BONE CEMENT: THE EFFECT OF MICROFIBERS MODIFICATION",
  year="2020",
  journal="Czech Chemical Society Symposium Series",
  volume="18",
  number="4",
  pages="255--255",
  publisher="Chemické listy",
  address="Praha",
  issn="2336-7210",
  url="http://www.insterdisciplinarymeeting.cz/shell/sbornik-2020.pdf",
  note="Abstract"
}