Detail publikačního výsledku

Bioinformatic Tools for Genotyping of Klebsiella pneumoniae Isolates

NYKRÝNOVÁ, M.; MADĚRÁNKOVÁ, D.; BEZDÍČEK, M.; LENGEROVÁ, M.; ŠKUTKOVÁ, H.

Originální název

Bioinformatic Tools for Genotyping of Klebsiella pneumoniae Isolates

Anglický název

Bioinformatic Tools for Genotyping of Klebsiella pneumoniae Isolates

Druh

Stať ve sborníku v databázi WoS či Scopus

Originální abstrakt

Nowadays we use multiple molecular typing methods capable of distinguishing bacteria strains. However, a majority of these methods are time-consuming, and associated costs are not negligible. Also, reproducibility of typing results is questionable. Therefore, we propose new typing methodology based on bioinformatics. In this paper, we present an algorithm that is at the core of the new method. It consists of multiple steps, such as measuring the quality of input data, identification of genes having high diversity and analysis of results employing clustering and phylogenetic trees. Obtained results are then compared with results from the mini-MLST method.

Anglický abstrakt

Nowadays we use multiple molecular typing methods capable of distinguishing bacteria strains. However, a majority of these methods are time-consuming, and associated costs are not negligible. Also, reproducibility of typing results is questionable. Therefore, we propose new typing methodology based on bioinformatics. In this paper, we present an algorithm that is at the core of the new method. It consists of multiple steps, such as measuring the quality of input data, identification of genes having high diversity and analysis of results employing clustering and phylogenetic trees. Obtained results are then compared with results from the mini-MLST method.

Klíčová slova

Bacterial strains, Genes, Genotyping, Klebsiella pneumoniae, Mini-MLST

Klíčová slova v angličtině

Bacterial strains, Genes, Genotyping, Klebsiella pneumoniae, Mini-MLST

Autoři

NYKRÝNOVÁ, M.; MADĚRÁNKOVÁ, D.; BEZDÍČEK, M.; LENGEROVÁ, M.; ŠKUTKOVÁ, H.

Vydáno

01.01.2019

ISBN

978-3-319-91210-3

Kniha

Information Technology in Biomedicine

Strany od

419

Strany do

428

Strany počet

10

URL

https://link.springer.com/chapter/10.1007/978-3-319-91211-0_37

BibTex

@inproceedings{BUT150417,
  author="Markéta {Jakubíčková} and Denisa {Maděránková} and Helena {Vítková} and Matěj {Bezdíček} and Martina {Lengerová}",
  title="Bioinformatic Tools for Genotyping of Klebsiella pneumoniae Isolates",
  booktitle="Information Technology in Biomedicine",
  year="2019",
  pages="419--428",
  doi="10.1007/978-3-319-91211-0\{_}37",
  isbn="978-3-319-91210-3",
  url="https://link.springer.com/chapter/10.1007/978-3-319-91211-0_37"
}