Design of tailored biodegradable implants: The effect of voltageon electrodeposited calcium phosphate Coatings on puremagnesium

Design of tailored biodegradable implants: The effect of voltageon electrodeposited calcium phosphate Coatings on puremagnesium

Článek WoS

Magnesium, as a biodegradable metal, offers great potential for use as a tempo-rary implant material, which dissolves in the course of bone tissue healing. It cansufficiently support the bone and promote the bone healing process. However, thecorrosion resistance of magnesium implants must be enhanced before its applica-tion in clinical practice. A promising approach of enhancing the corrosion resis-tance is deposition of bioactive coating, which can reduce the corrosion rate ofthe implants and promote bone healing. Therefore, a well‐designed substrate‐coat-ing system allowing a good control of the degradation behavior is highly desir -able for tailored implants for specific groups of patients with particular needs. Inthis con tribution, the influence of coating formation conditions on the charact eris-tics of potentiostatically elect rodeposited CaP coatings on magnesium substratewas evaluated. Results showed that potential variation led to formation of coat-ings with the same chemical composition, but very different morphologies.Parameters that mostly influence the coating performance, such as the thickness,uniformity, deposits size, and orientation, varied from produced coating to coat-ing. These characteristics of CaP coatings on magnesium were controlled by coat-ing formation potential, and it was demonstrated that the electrodeposition couldbe a promising coating technique for production of tailored magnesium‐ CaPimplants.

Magnesium, as a biodegradable metal, offers great potential for use as a tempo-rary implant material, which dissolves in the course of bone tissue healing. It cansufficiently support the bone and promote the bone healing process. However, thecorrosion resistance of magnesium implants must be enhanced before its applica-tion in clinical practice. A promising approach of enhancing the corrosion resis-tance is deposition of bioactive coating, which can reduce the corrosion rate ofthe implants and promote bone healing. Therefore, a well‐designed substrate‐coat-ing system allowing a good control of the degradation behavior is highly desir -able for tailored implants for specific groups of patients with particular needs. Inthis con tribution, the influence of coating formation conditions on the charact eris-tics of potentiostatically elect rodeposited CaP coatings on magnesium substratewas evaluated. Results showed that potential variation led to formation of coat-ings with the same chemical composition, but very different morphologies.Parameters that mostly influence the coating performance, such as the thickness,uniformity, deposits size, and orientation, varied from produced coating to coat-ing. These characteristics of CaP coatings on magnesium were controlled by coat-ing formation potential, and it was demonstrated that the electrodeposition couldbe a promising coating technique for production of tailored magnesium‐ CaPimplants.

biodegradation; calcium phosphate; coatings; electrodeposition; magnesium

biodegradation; calcium phosphate; coatings; electrodeposition; magnesium

HORYNOVÁ, M.; REMEŠOVÁ, M.; KLAKURKOVÁ, L.; DVOŘÁK, K.; ROČŇÁKOVÁ, I.; YAN, S.; ČELKO, L.; SONG, G. L.

2019

01.01.2019

The American Ceramic Society

Spojené státy americké

0002-7820

JOURNAL OF THE AMERICAN CERAMIC SOCIETY

102

1

Spojené státy americké

123

135

13

https://onlinelibrary.wiley.com/doi/abs/10.1111/jace.15888

http://hdl.handle.net/11012/245259

2018-ART-13--JACE-Design of tailored biodegradable implants-hor-rem-klak-dv-roc--BUT_LIB
jace.15888-accepted