Detail publikačního výsledku

Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics

VACULOVIČOVÁ, M.; ŠMERKOVÁ, K.; PEKÁRKOVÁ, J.; HUBÁLEK, J.; ADAM, V.; KIZEK, R.

Originální název

Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics

Anglický název

Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics

Druh

Článek WoS

Originální abstrakt

Cisplatin, carboplatin, and oxaliplatin represent three generations of platinum based drugs applied successfully for cancer treatment. As a consequence of the employment of platinum based cytostatics in the cancer treatment, it became necessary to study the mechanism of their action. Current accepted opinion is the formation of Pt-DNA adducts, but the mechanism of their formation is still unclear. Nanomaterials, as a progressively developing branch, can offer a tool for studying the interactions of these drugs with DNA

Anglický abstrakt

Cisplatin, carboplatin, and oxaliplatin represent three generations of platinum based drugs applied successfully for cancer treatment. As a consequence of the employment of platinum based cytostatics in the cancer treatment, it became necessary to study the mechanism of their action. Current accepted opinion is the formation of Pt-DNA adducts, but the mechanism of their formation is still unclear. Nanomaterials, as a progressively developing branch, can offer a tool for studying the interactions of these drugs with DNA

Klíčová slova

Capillary electrophoresis, DNA, Gel electrophoresis, Platinum cytostatic drugs, Quantum dots

Klíčová slova v angličtině

Capillary electrophoresis, DNA, Gel electrophoresis, Platinum cytostatic drugs, Quantum dots

Autoři

VACULOVIČOVÁ, M.; ŠMERKOVÁ, K.; PEKÁRKOVÁ, J.; HUBÁLEK, J.; ADAM, V.; KIZEK, R.

Rok RIV

2014

Vydáno

01.03.2013

Nakladatel

Wiley

Místo

Německo

ISSN

0173-0835

Periodikum

ELECTROPHORESIS

Svazek

34

Číslo

6

Stát

Spolková republika Německo

Strany od

801

Strany do

808

Strany počet

8

BibTex

@article{BUT100726,
  author="Markéta {Vaculovičová} and Kristýna {Šmerková} and Jana {Pekárková} and Jaromír {Hubálek} and Vojtěch {Adam} and René {Kizek}",
  title="Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics",
  journal="ELECTROPHORESIS",
  year="2013",
  volume="34",
  number="6",
  pages="801--808",
  doi="10.1002/elps.201200664",
  issn="0173-0835"
}