Detail publikačního výsledku

Synthesis of CdTe/ZnZ Core/Shell Quantum Dots and Their In Vitro Toxicity Assessment

PEKÁRKOVÁ, J.; FOHLEROVÁ, Z.; DRBOHLAVOVÁ, J.; PEKÁREK, J.; MAJZLÍKOVÁ, P.; PRÁŠEK, J.; HUBÁLEK, J.

Originální název

Synthesis of CdTe/ZnZ Core/Shell Quantum Dots and Their In Vitro Toxicity Assessment

Anglický název

Synthesis of CdTe/ZnZ Core/Shell Quantum Dots and Their In Vitro Toxicity Assessment

Druh

Stať ve sborníku v databázi WoS či Scopus

Originální abstrakt

Water soluble CdTe core a CdTe/ZnS core/shell QDs stabilized with different ligands (3-mercaptoacetic acid, thioglycolic acid, glutathione and mercaptosuccinic acid) were prepared by a simple method using Na2TeO3 and CdCl2. For comparison, ZnSe and ZnSe/ZnS QDs were also prepared. QDs cytotoxicity on Human Embryonic Kidney cells (HEK 293) was performed using MTT (3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) viability assay. Single core CdTe QDs were found to have severe toxic effects on cells due to the absence of a zinc sulfide shell, which currently decreases the toxicity of QDs.

Anglický abstrakt

Water soluble CdTe core a CdTe/ZnS core/shell QDs stabilized with different ligands (3-mercaptoacetic acid, thioglycolic acid, glutathione and mercaptosuccinic acid) were prepared by a simple method using Na2TeO3 and CdCl2. For comparison, ZnSe and ZnSe/ZnS QDs were also prepared. QDs cytotoxicity on Human Embryonic Kidney cells (HEK 293) was performed using MTT (3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) viability assay. Single core CdTe QDs were found to have severe toxic effects on cells due to the absence of a zinc sulfide shell, which currently decreases the toxicity of QDs.

Klíčová slova

Quantum dots, core/shell, toxicity, MTT

Klíčová slova v angličtině

Quantum dots, core/shell, toxicity, MTT

Autoři

PEKÁRKOVÁ, J.; FOHLEROVÁ, Z.; DRBOHLAVOVÁ, J.; PEKÁREK, J.; MAJZLÍKOVÁ, P.; PRÁŠEK, J.; HUBÁLEK, J.

Vydáno

05.11.2014

Nakladatel

Tanger, Ltd.

Místo

Ostrava

ISBN

978-80-87294-53-6

Kniha

6 th International conference Nanocon 2014

Edice

1

Strany od

664

Strany do

669

Strany počet

6

BibTex

@inproceedings{BUT111379,
  author="Jana {Pekárková} and Zdenka {Fohlerová} and Jana {Drbohlavová} and Jan {Pekárek} and Petra {Majzlíková} and Jan {Prášek} and Jaromír {Hubálek}",
  title="Synthesis of CdTe/ZnZ Core/Shell Quantum Dots and Their In Vitro Toxicity Assessment",
  booktitle="6 th International conference Nanocon 2014",
  year="2014",
  series="1",
  number="1",
  pages="664--669",
  publisher="Tanger, Ltd.",
  address="Ostrava",
  isbn="978-80-87294-53-6"
}