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PEKÁRKOVÁ, J.; FOHLEROVÁ, Z.; DRBOHLAVOVÁ, J.; PEKÁREK, J.; MAJZLÍKOVÁ, P.; PRÁŠEK, J.; HUBÁLEK, J.
Original Title
Synthesis of CdTe/ZnZ Core/Shell Quantum Dots and Their In Vitro Toxicity Assessment
English Title
Type
Paper in proceedings (conference paper)
Original Abstract
Water soluble CdTe core a CdTe/ZnS core/shell QDs stabilized with different ligands (3-mercaptoacetic acid, thioglycolic acid, glutathione and mercaptosuccinic acid) were prepared by a simple method using Na2TeO3 and CdCl2. For comparison, ZnSe and ZnSe/ZnS QDs were also prepared. QDs cytotoxicity on Human Embryonic Kidney cells (HEK 293) was performed using MTT (3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) viability assay. Single core CdTe QDs were found to have severe toxic effects on cells due to the absence of a zinc sulfide shell, which currently decreases the toxicity of QDs.
English abstract
Keywords
Quantum dots, core/shell, toxicity, MTT
Key words in English
Authors
Released
05.11.2014
Publisher
Tanger, Ltd.
Location
Ostrava
ISBN
978-80-87294-53-6
Book
6 th International conference Nanocon 2014
Edition
1
Pages from
664
Pages to
669
Pages count
6
BibTex
@inproceedings{BUT111379, author="Jana {Pekárková} and Zdenka {Fohlerová} and Jana {Drbohlavová} and Jan {Pekárek} and Petra {Majzlíková} and Jan {Prášek} and Jaromír {Hubálek}", title="Synthesis of CdTe/ZnZ Core/Shell Quantum Dots and Their In Vitro Toxicity Assessment", booktitle="6 th International conference Nanocon 2014", year="2014", series="1", number="1", pages="664--669", publisher="Tanger, Ltd.", address="Ostrava", isbn="978-80-87294-53-6" }