Detail publikace

Oleaginous Yeast Extracts and Their Possible Effects on Human Health.

VYSOKÁ, M. SZOTKOWSKI, M. SLANINOVÁ, E. DZURICKÁ, L. STREČANSKÁ, P. BLAŽKOVÁ, J. MÁROVÁ, I.

Originální název

Oleaginous Yeast Extracts and Their Possible Effects on Human Health.

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Four non-conventional oleaginous and pigmented yeast strains of Metschnikowia pulcherrima, Cystofilobasidium infirmominiatum, Phaffia rhodozyma, and Rhodotorula kratochvilovae were used in this study. Complex yeast extracts were prepared and tested for biological activity, safety, and effect on human health. In this paper, we measured the antioxidant activity and antimicrobial effect of yeast biomass as a whole and their extracts to compare the influence of carotenoids and other bioactive substances in the studied biomass. All yeast extracts exhibited a significant dose-dependent antimicrobial effect against both G+ and G- bacteria and had a strong antioxidant effect. No cytotoxicity in the mouse melanoma B16F1 cell line was found in concentrations up to 20% of rehydrated biomass in cell medium. All of the extracts were cytotoxic at a concentration of 5 mg of extract/g of dry biomass. All the pigmented yeast extracts showed some positive results for apoptosis of murine melanoma cell lines and are therefore strong candidates positively effect human health. Red yeast cell biomass is a prospective material with many attractive biological functions and can be used in the food industry, as a pharmaceutical material, or in the feed industry.

Klíčová slova

oleaginous yeast; pigmented yeasts; bioactive compounds; antimicrobial effect; cytotoxic effect; apoptosis

Autoři

VYSOKÁ, M.; SZOTKOWSKI, M.; SLANINOVÁ, E.; DZURICKÁ, L.; STREČANSKÁ, P.; BLAŽKOVÁ, J.; MÁROVÁ, I.

Vydáno

16. 2. 2023

Nakladatel

MDPI

ISSN

2076-2607

Periodikum

Microorganisms

Ročník

11

Číslo

2

Stát

Švýcarská konfederace

Strany od

1

Strany do

13

Strany počet

13

URL

https://www.mdpi.com/2076-2607/11/2/492

Plný text v Digitální knihovně

http://hdl.handle.net/11012/213541

BibTex

@article{BUT183470,
  author="Marie {Vysoká} and Martin {Szotkowski} and Eva {Slaninová} and Lucia {Dzurická} and Paulína {Strečanská} and Jana {Blažková} and Ivana {Márová}",
  title="Oleaginous Yeast Extracts and Their Possible Effects on Human Health.",
  journal="Microorganisms",
  year="2023",
  volume="11",
  number="2",
  pages="1--13",
  doi="10.3390/microorganisms11020492",
  issn="2076-2607",
  url="https://www.mdpi.com/2076-2607/11/2/492"
}