Detail publikace

Plasma-coated PCL scaffolds with immobilized platelet-rich plasma enhance the wound healing in diabetics mice

Solovieva, AO. Permyakova, ES. Ershov, KI. Bakhareva, KI. Miroshnichenko, SM. Kiryukhantsev-Korneev, PV. Konopatsky, AS. Polcak, J. Shtansky, DV. Manakhov, AM

Originální název

Plasma-coated PCL scaffolds with immobilized platelet-rich plasma enhance the wound healing in diabetics mice

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

COOH plasma polymer layers deposited onto polycaprolactone (PCL) nanofibers by plasma polymerization of CO2 and C2H4 in the Ar atmosphere were obtained and tested for diabetic wound healing. Simply by changing the deposition time, very different morphologies of coated PCL nanofibers were achieved. In vivo tests revealed that by applying modified nanofibers for 10 days, wound healing accelerated by 32.1%. Compared to a controlled wound characterized by an acute inflammatory process, wounds covered with nanofibers with platelet-rich plasma demonstrated complete healing with a high percentage of collagen fibers on Day 19.

Klíčová slova

in vivo; polycaprolactone; type 2 diabetes mellitus; wound healing; XPS

Autoři

Solovieva, AO.; Permyakova, ES.; Ershov, KI.; Bakhareva, KI.; Miroshnichenko, SM.; Kiryukhantsev-Korneev, PV.; Konopatsky, AS.; Polcak, J.; Shtansky, DV.; Manakhov, AM

Vydáno

1. 7. 2022

ISSN

1612-8869

Periodikum

Plasma Processes and Polymers

Ročník

19

Číslo

7

Stát

Spolková republika Německo

Strany od

e2200032

Strany počet

12

URL

https://onlinelibrary.wiley.com/doi/10.1002/ppap.202200032

BibTex

@article{BUT178560,
  author="Solovieva, AO. and Permyakova, ES. and Ershov, KI. and Bakhareva, KI. and Miroshnichenko, SM. and Kiryukhantsev-Korneev, PV. and Konopatsky, AS. and Polcak, J. and Shtansky, DV. and Manakhov, AM",
  title="Plasma-coated PCL scaffolds with immobilized platelet-rich plasma enhance the wound healing in diabetics mice",
  journal="Plasma Processes and Polymers",
  year="2022",
  volume="19",
  number="7",
  pages="12",
  doi="10.1002/ppap.202200032",
  issn="1612-8869",
  url="https://onlinelibrary.wiley.com/doi/10.1002/ppap.202200032"
}