Detail publikace

Effects of the administration of different buffered balanced crystalloid solutions on acid-base and electrolyte status in dogs with gastric dilation-volvulus syndrome: a randomized clinical trial

RAUŠEROVÁ-LEXMAULOVÁ, L. PROKEŠOVÁ, B. BLOŽOŇOVÁ, A. VÁŇOVÁ-UHRÍKOVÁ, I. ŘEHÁKOVÁ, K. FUSEK, M.

Originální název

Effects of the administration of different buffered balanced crystalloid solutions on acid-base and electrolyte status in dogs with gastric dilation-volvulus syndrome: a randomized clinical trial

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Objective: To investigate the effect of three different buffered balanced crystalloid solutions on acid–base status and electrolyte concentrations in dogs with gastric dilation–volvulus (GDV) syndrome. Methods: The study design was a prospective, randomized clinical trial of 40 dogs. The dogs were randomly assigned to one of three groups according to the fluid used: Hartmann’s solution (H), Plasmalyte (PL), and Ringerfundin (RF). Hemoglobin, albumin, lactate, electrolyte, and acid–base parameters were determined before fluid administration (T0) and at the end of surgery (T1). Results were assessed by one-way ANOVA, Fisher’s exact test, the Wilcoxon signed-rank test, the Kruskal–Wallis test, and a linear mixed-effect regression model. A significance level of 0.05 was used in all analyses. Results: Bicarbonate and base excess (BE) levels increased and chloride concentration decreased in the PL group; in contrast, strong ion difference apparent (SIDapp) decreased and chloride concentration increased in the RF group. The mixed-effect model confirmed a significant interaction between the type of solution and time on the changes in bicarbonate, BE, anion gap (AG), SIDapp, and chloride levels. Clinical significance: Significantly different effects in acid–base parameters were observed in dogs after intravenous administration of H, PL, and RF. However, clinical significance of these changes is lacking, requiring further investigation in a larger randomized controlled clinical trial.

Klíčová slova

bicarbonate precursor, acid–base disorders, correction, shock, fluid therapy

Autoři

RAUŠEROVÁ-LEXMAULOVÁ, L.; PROKEŠOVÁ, B.; BLOŽOŇOVÁ, A.; VÁŇOVÁ-UHRÍKOVÁ, I.; ŘEHÁKOVÁ, K.; FUSEK, M.

Vydáno

19. 1. 2022

ISSN

1938-9736

Periodikum

TOP COMPANION ANIM M

Ročník

46

Číslo

1

Stát

Spojené státy americké

Strany od

1

Strany do

10

Strany počet

10

URL

https://www.sciencedirect.com/science/article/pii/S1938973621001033

BibTex

@article{BUT175090,
  author="Leona {Raušerová-Lexmaulová} and Barbara {Prokešová} and Aneta {Bložoňová} and Ivana {Váňová-Uhríková} and Kristína {Řeháková} and Michal {Fusek}",
  title="Effects of the administration of different buffered balanced crystalloid solutions on acid-base and electrolyte status in dogs with gastric dilation-volvulus syndrome: a randomized clinical trial",
  journal="TOP COMPANION ANIM M",
  year="2022",
  volume="46",
  number="1",
  pages="1--10",
  doi="10.1016/j.tcam.2021.100613",
  issn="1938-9736",
  url="https://www.sciencedirect.com/science/article/pii/S1938973621001033"
}