Detail publikace

A Perspective Combination Quantum Dots and Silica Nanoparticies: for Bioconjugation with Antibodies used in Immunosensors for Detection of Human Alpha-Fetoprotein

KOVAROVA, A. DRBOHLAVOVÁ, J. BÍLKOVÁ, Z. KORECKA, L.

Originální název

A Perspective Combination Quantum Dots and Silica Nanoparticies: for Bioconjugation with Antibodies used in Immunosensors for Detection of Human Alpha-Fetoprotein

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

The combination of quantum dots (QDs) with silica nanoparticles (SiNPs) as promising signal-generating label of antibodies used in electrochemical immunosensor is described. QDs-modified silica nanoparticles were conjugated with specific antibodies targeted to alpha-fetoprotein (AFP) to a creation of anti-AFP-SiNPs-QDs IgG conjugate for subsequent exploitation in quantum dot-linked immunosorbent assay (QLISA). Square wave anodic stripping voltammetry (SWASV) on mercury or bismuth film modified carbon screen-printed three-electrode sensors was used as a detection method. Insertion of nanoparticles to this system led to the achievement of higher current responses compare to results obtained with QDs only. Therefore, the sensitivity of complete immunoassay could be significantly improved.

Klíčová slova

Quantum dots; Silica nanoparticles; Antibody label Electrochemical immunosensors; SWASV

Autoři

KOVAROVA, A.; DRBOHLAVOVÁ, J.; BÍLKOVÁ, Z.; KORECKA, L.

Vydáno

15. 5. 2017

ISBN

978-80-905221-5-2

Kniha

XXXVII MODERNI ELEKTROCHEMICKE METODY

Strany od

108

Strany do

112

Strany počet

5

BibTex

@inproceedings{BUT170241,
  author="Aneta {Kovarova} and Jana {Drbohlavová} and Zuzana {Bílková} and Lucie {Korecka}",
  title="A Perspective Combination Quantum Dots and Silica Nanoparticies: for Bioconjugation with Antibodies used in Immunosensors for Detection of Human Alpha-Fetoprotein",
  booktitle="XXXVII MODERNI ELEKTROCHEMICKE METODY",
  year="2017",
  pages="108--112",
  isbn="978-80-905221-5-2"
}