Detail publikace

Femoral bone defect healing using two novel biocompatible degradable materials

SRNEC, R. NEČASOVÁ, A. PROKS, P. SKORIC, M. FILIPEJOVÁ, Z. VOJTOVÁ, L. NEČAS, A.

Originální název

Femoral bone defect healing using two novel biocompatible degradable materials

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

This study was conducted as an in vivo experiment in adult miniature pigs with the aim to test two new biomaterials. An iatrogenic defect was made into the central femoral diaphysis in the experimental animals and subsequently fixated by bridging plate osteosynthesis. Into the defect we implanted a cancellous autograft (control group), a pasty injectable scaffold (EXP A), anda porous 3D cylinder (EXP B). Radiological examination was performed in all animals at 0, 10, 20, 30 weeks after surgical procedure and histological assessment was performed. In the newly formed bone the osteoblastic activity was monitored. In terms of radiology, the most effective method was observed in the control group (completely healed 100%) compared to experimental groups EXP A (70.0%) and EXP B (62.5%).

Klíčová slova

Pig, biomaterial, scaffold, animal model, composite, phosphate

Autoři

SRNEC, R.; NEČASOVÁ, A.; PROKS, P.; SKORIC, M.; FILIPEJOVÁ, Z.; VOJTOVÁ, L.; NEČAS, A.

Vydáno

26. 5. 2020

Nakladatel

Acta Veterinaria Brno

Místo

Brno

ISSN

1801-7576

Periodikum

ACTA VETERINARIA BRNO

Ročník

89

Číslo

2

Stát

Česká republika

Strany od

163

Strany do

169

Strany počet

7

URL

https://actavet.vfu.cz/89/2/0163/

Plný text v Digitální knihovně

http://hdl.handle.net/11012/196653

BibTex

@article{BUT166347,
  author="Robert {Srnec} and Andrea {Nečasová} and Pavel {Proks} and Misa {Skoric} and Zita {Filipejová} and Lucy {Vojtová} and Alois {Nečas}",
  title="Femoral bone defect healing using two novel biocompatible degradable materials",
  journal="ACTA VETERINARIA BRNO",
  year="2020",
  volume="89",
  number="2",
  pages="163--169",
  doi="10.2754/avb202089020163",
  issn="1801-7576",
  url="https://actavet.vfu.cz/89/2/0163/"
}

Dokumenty

actavet_2020089020163.pdf