Detail publikace

Femoral bone defect healing using two novel biocompatible degradable materials

SRNEC, R. NEČASOVÁ, A. PROKS, P. SKORIC, M. FILIPEJOVÁ, Z. VOJTOVÁ, L. NEČAS, A.

Originální název

Femoral bone defect healing using two novel biocompatible degradable materials

Anglický název

Femoral bone defect healing using two novel biocompatible degradable materials

Jazyk

en

Originální abstrakt

This study was conducted as an in vivo experiment in adult miniature pigs with the aim to test two new biomaterials. An iatrogenic defect was made into the central femoral diaphysis in the experimental animals and subsequently fixated by bridging plate osteosynthesis. Into the defect we implanted a cancellous autograft (control group), a pasty injectable scaffold (EXP A), anda porous 3D cylinder (EXP B). Radiological examination was performed in all animals at 0, 10, 20, 30 weeks after surgical procedure and histological assessment was performed. In the newly formed bone the osteoblastic activity was monitored. In terms of radiology, the most effective method was observed in the control group (completely healed 100%) compared to experimental groups EXP A (70.0%) and EXP B (62.5%).

Anglický abstrakt

This study was conducted as an in vivo experiment in adult miniature pigs with the aim to test two new biomaterials. An iatrogenic defect was made into the central femoral diaphysis in the experimental animals and subsequently fixated by bridging plate osteosynthesis. Into the defect we implanted a cancellous autograft (control group), a pasty injectable scaffold (EXP A), anda porous 3D cylinder (EXP B). Radiological examination was performed in all animals at 0, 10, 20, 30 weeks after surgical procedure and histological assessment was performed. In the newly formed bone the osteoblastic activity was monitored. In terms of radiology, the most effective method was observed in the control group (completely healed 100%) compared to experimental groups EXP A (70.0%) and EXP B (62.5%).

Plný text v Digitální knihovně

Dokumenty

BibTex


@article{BUT166347,
  author="Robert {Srnec} and Andrea {Nečasová} and Pavel {Proks} and Misa {Skoric} and Zita {Filipejová} and Lucy {Vojtová} and Alois {Nečas}",
  title="Femoral bone defect healing using two novel biocompatible degradable materials",
  annote="This study was conducted as an in vivo experiment in adult miniature pigs with the aim to test two new biomaterials. An iatrogenic defect was made into the central femoral diaphysis in the experimental animals and subsequently fixated by bridging plate osteosynthesis. Into the defect we implanted a cancellous autograft (control group), a pasty injectable scaffold (EXP A), anda porous 3D cylinder (EXP B). Radiological examination was performed in all animals at 0, 10, 20, 30 weeks after surgical procedure and histological assessment was performed. In the newly formed bone the osteoblastic activity was monitored. In terms of radiology, the most effective method was observed in the control group (completely healed 100%) compared to experimental groups EXP A (70.0%) and EXP B (62.5%).",
  address="Acta Veterinaria Brno",
  chapter="166347",
  doi="10.2754/avb202089020163",
  howpublished="online",
  institution="Acta Veterinaria Brno",
  number="2",
  volume="89",
  year="2020",
  month="may",
  pages="163--169",
  publisher="Acta Veterinaria Brno",
  type="journal article in Web of Science"
}