Detail publikace

TEST OF COMPLEX NANOSTRUCTURES AS GENE DELIVERY SYSTEM TO CARDIAC CELLS

SKOPALÍK, J. PRŮCHA, J. SEKORA, J. ČMIEL, V. PARAK, T. MASEK, j.

Originální název

TEST OF COMPLEX NANOSTRUCTURES AS GENE DELIVERY SYSTEM TO CARDIAC CELLS

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Various nanostructures, including liposomes, dendrimers, polymers, carbon or silicon materials, and metal nanoparticles seems to be evaluated as carriers in different gene delivery systems. Muscle cells are target of modern gene medicine, due to of the much pathology (arrhythmias, channels pathological mutation, abnormal apoptosis) with limited curability by traditional drugs. The zeta potential of the muscle cells were identified by non-traditional method of DLS. This was starting point to setting of parameters for experimental liposome, the liposome surface charge have been tested and modified by cationic plasmid and final complex was evaluated as delivery system of DNA into the muscle cardiac cells.

Klíčová slova

Nanoliposom; nanoparticle; transfection; zeta potential; cell engineering; regenerative medicine

Autoři

SKOPALÍK, J.; PRŮCHA, J.; SEKORA, J.; ČMIEL, V.; PARAK, T.; MASEK, j.

Vydáno

28. 12. 2020

Nakladatel

TANGER LTD

Místo

SLEZSKA

ISBN

978-80-87294-98-7

Kniha

NANOCON

Strany od

342

Strany do

346

Strany počet

5

BibTex

@inproceedings{BUT166063,
  author="SKOPALÍK, J. and PRŮCHA, J. and SEKORA, J. and ČMIEL, V. and PARAK, T. and MASEK, j.",
  title="TEST OF COMPLEX NANOSTRUCTURES AS GENE DELIVERY SYSTEM TO CARDIAC CELLS",
  booktitle="NANOCON",
  year="2020",
  pages="342--346",
  publisher="TANGER LTD",
  address="SLEZSKA",
  doi="10.37904/nanocon.2020.3757",
  isbn="978-80-87294-98-7"
}