Detail publikace

Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction

HYNEK, D. TMEJOVÁ, K. TRNKOVÁ, L. HUBÁLEK, J. ADAM, V. KIZEK, R.

Originální název

Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction

Typ

kapitola v knize

Jazyk

angličtina

Originální abstrakt

Application of electrochemical methods for protein determination was discovered in the thirties of the last century. Rudolf Brdicka was one who focused his attention to the protein electrochemical determination and used discovered analytical method for clinical purposes. Brdicka way of protein detection was based on the specific reaction between thiol group of proteins with Brdicka solution. Metallothionein (MT) as a low-molecular mass protein with high thiols content seems to be ideal target for such detection. This protein is involved in heavy metals homeostasis due to their chelation centers in MT structure.

Klíčová slova

metallothionein, Brdicka reaction, thiol compound, mercury electrode, tumour diseases, automation

Autoři

HYNEK, D.; TMEJOVÁ, K.; TRNKOVÁ, L.; HUBÁLEK, J.; ADAM, V.; KIZEK, R.

Rok RIV

2013

Vydáno

1. 6. 2013

Nakladatel

Nova Science Publisher, Inc.

ISBN

978-1-62948-057-2

Kniha

Voltammetry: Theory, Types and Applications

Číslo edice

1

Strany od

1

Strany do

12

Strany počet

12

URL

http://web2.mendelu.cz/af_239_nanotech/data/pub/Kizek%20from%20978-1-62948-057-2.pdf

BibTex

@inbook{BUT101248,
  author="David {Hynek} and Kateřina {Tmejová} and Libuše {Trnková} and Jaromír {Hubálek} and Vojtěch {Adam} and René {Kizek}",
  title="Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction",
  booktitle="Voltammetry: Theory, Types and Applications",
  year="2013",
  publisher="Nova Science Publisher, Inc.",
  edition="1",
  pages="1--12",
  isbn="978-1-62948-057-2",
  url="http://web2.mendelu.cz/af_239_nanotech/data/pub/Kizek%20from%20978-1-62948-057-2.pdf"
}