Detail publikačního výsledku

Microfluidic chip coupled with modified paramagnetic particles for sarcosine isolation in urine

ZÍTKA, O.; CERNEI, N.; HEGER, Z.; MATOUŠEK, M.; KOPEL, P.; KYNICKÝ, J.; MASAŘÍK, M.; KIZEK, R.; ADAM, V.

Originální název

Microfluidic chip coupled with modified paramagnetic particles for sarcosine isolation in urine

Anglický název

Microfluidic chip coupled with modified paramagnetic particles for sarcosine isolation in urine

Druh

Článek WoS

Originální abstrakt

Carcinoma of prostate (CaP) is the second most frequent malignant tumor occurring in men in Europe. Currently there is discussion on a wide range of potential CaP markers. One of them - nonprotein amino acid sarcosine, also known as N-methylglycine was chosen as a challenge for the development of microfluidic system with isolation by modified paramagnetic microparticles. Therefore, the aim of this study was to design a low-cost, simple, and rapidmicrofluidic system based on sarcosine isolation with modified paramagnetic microparticles and subsequent analysis on the ion exchange LC.

Anglický abstrakt

Carcinoma of prostate (CaP) is the second most frequent malignant tumor occurring in men in Europe. Currently there is discussion on a wide range of potential CaP markers. One of them - nonprotein amino acid sarcosine, also known as N-methylglycine was chosen as a challenge for the development of microfluidic system with isolation by modified paramagnetic microparticles. Therefore, the aim of this study was to design a low-cost, simple, and rapidmicrofluidic system based on sarcosine isolation with modified paramagnetic microparticles and subsequent analysis on the ion exchange LC.

Klíčová slova

Ion exchange chromatography, Magnetic nanoparticles, Microfluidic separation, Prostate cancer, Surface modification

Klíčová slova v angličtině

Ion exchange chromatography, Magnetic nanoparticles, Microfluidic separation, Prostate cancer, Surface modification

Autoři

ZÍTKA, O.; CERNEI, N.; HEGER, Z.; MATOUŠEK, M.; KOPEL, P.; KYNICKÝ, J.; MASAŘÍK, M.; KIZEK, R.; ADAM, V.

Rok RIV

2014

Vydáno

01.09.2013

ISSN

0173-0835

Periodikum

ELECTROPHORESIS

Svazek

34

Číslo

18

Stát

Spolková republika Německo

Strany od

2639

Strany do

2647

Strany počet

9

BibTex

@article{BUT103908,
  author="Ondřej {Zítka} and Natalia Vladimirovna {Cernei} and Zbyněk {Heger} and Miroslav {Matoušek} and Pavel {Kopel} and Jindřich {Kynický} and Michal {Masařík} and René {Kizek} and Vojtěch {Adam}",
  title="Microfluidic chip coupled with modified paramagnetic particles for sarcosine isolation in urine",
  journal="ELECTROPHORESIS",
  year="2013",
  volume="34",
  number="18",
  pages="2639--2647",
  doi="10.1002/elps.201300114",
  issn="0173-0835"
}