Detail publikace

Perceptual Features as Markers of Parkinson’s Disease: The Issue of Clinical Interpretability

MEKYSKA, J. SMÉKAL, Z. GALÁŽ, Z. MŽOUREK, Z. REKTOROVÁ, I. FAÚNDEZ ZANUY, M. LOPEZ-DE-IPINA, K.

Originální název

Perceptual Features as Markers of Parkinson’s Disease: The Issue of Clinical Interpretability

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Up to 90 % of patients with Parkinson’s disease (PD) suffer from hypokinetic dysathria (HD) which is also manifested in the field of phonation. Clinical signs of HD like monoloudness, monopitch or hoarse voice are usually quantified by conventional clinical interpretable features (jitter, shimmer, harmonic-to-noise ratio, etc.). This paper provides large and robust insight into perceptual analysis of 5 Czech vowels of 84 PD patients and proves that despite the clinical inexplicability the perceptual features outperform the conventional ones, especially in terms of discrimination power (classification accuracy ACC=92 %, sensitivity SEN=93 %, specificity SPE=92 %) and partial correlation with clinical scores like UPDRS (Unified Parkinson’s disease rating scale), MMSE (Mini-mental state examination) or FOG (Freezing of gait questionnaire), where p < 0.0001.

Klíčová slova

Perceptual features, perceptual analysis, Parkinson’s disease, hypokinetic dysarthria, speech processing

Autoři

MEKYSKA, J.; SMÉKAL, Z.; GALÁŽ, Z.; MŽOUREK, Z.; REKTOROVÁ, I.; FAÚNDEZ ZANUY, M.; LOPEZ-DE-IPINA, K.

Vydáno

23. 1. 2016

Nakladatel

Springer International Publishing

Místo

Switzerland

ISBN

978-3-319-28107-0

Kniha

Recent Advances in Nonlinear Speech Processing

Strany od

83

Strany do

91

Strany počet

9

BibTex

@inproceedings{BUT123875,
  author="Jiří {Mekyska} and Zdeněk {Smékal} and Zoltán {Galáž} and Zdeněk {Mžourek} and Irena {Rektorová} and Marcos {Faúndez Zanuy} and Karmele {Lopez-de-Ipina}",
  title="Perceptual Features as Markers of Parkinson’s Disease: The Issue of Clinical Interpretability",
  booktitle="Recent Advances in Nonlinear Speech Processing",
  year="2016",
  pages="83--91",
  publisher="Springer International Publishing",
  address="Switzerland",
  doi="10.1007/978-3-319-28109-4\{_}9",
  isbn="978-3-319-28107-0"
}