Course detail

Cell and Tissue Engineering

FEKT-MPAN-TBIAcad. year: 2026/2027

The subject "Technology in cell engineering" introduces students to the methods, technologies and instrumentation used in the fields of cell and tissue engineering in laboratories and research. 

Language of instruction

English

Number of ECTS credits

4

Mode of study

Not applicable.

Guarantor

doc. Mgr. Zdenka Fohlerová, Ph.D.

Department

Department of Biomedical Engineering (UBMI)

Rules for evaluation and completion of the course

The final grade for the course will be determined by the scores obtained from the midterm tests and the activity
exercises (max. 20 points in total) and the final written examination (max. 80 points).  
Only students who have been awarded credit may take the final exam.
- obtaining at least 15 points in the laboratory exercises, including points for the continuous written tests,
- a non-zero score on the continuous written tests,
- a non-zero score on the protocols or homework assignments,
- meeting full attendance requirements.

More detailed conditions for successful completion of the course are set out in the annually updated decree of the course coordinator.  

  

Aims

The aim of the course is to provide students with knowledge of technologies and methods used in laboratories focused on cell and tissue engineering.  

Study aids

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Alberts B., Johnson A., Walter P.: Molecular Biology of the Cell.
Ankur Singh, Akhilesh K. Gaharwar: Microscale Technologies for Cell Engineering
Bengt Nölting: Methods in Modern Biophysics
José Luis R. Arrondo, Alicia Alonso: Advanced Techniques in Biophysics.

Recommended reading

Not applicable.

Classification of course in study plans

  • Programme MPA-BTB Master's 2 year of study, summer semester, compulsory
  • Programme MPCN-BTB Master's 2 year of study, summer semester, compulsory-optional
  • Programme MPAN-BIO Master's 2 year of study, summer semester, compulsory

  • Programme MPCN-BIO Master's

    specialization MPC-BIO_TECH , 2 year of study, summer semester, compulsory-optional

Type of course unit

 

Lecture

26 hours, optionally

Teacher / Lecturer

doc. Mgr. Zdenka Fohlerová, Ph.D.

Syllabus

1 – Cell and Tissue Engineering Fundamentals

2 – Biomaterials in Tissue Engineering

3 – Scaffold Design & Fabrication for Tissue Engineering

4 – Cell Culture Techniques & Bioreactors

5 – Stem Cells in Regenerative Medicine

6 – Mechanotransduction in Cell Engineering

7 – Blood Vessel and Skin Tissue Engineering

8 – Bone and Cartilage Tissue Engineering

9 – Organ–on–a–Chip Systems

10 – Cell-biomaterial Interaction and Characterization

11 – Characterization Techniques of Biomaterials and Cells

12 – Clinical Translation & Regulatory Aspects

Laboratory exercise

9 hours, compulsory

Teacher / Lecturer

doc. Mgr. Zdenka Fohlerová, Ph.D.

Syllabus

1. Cultivation of cells. Preparation of hydrogel and seeding of cells on hydrogel. Degradation of hydrogel.

2. Swelling of hydrogel. Evaluation of hydrogel swelling and degradation. Microscopic evaluation of cells on hydrogel (VIS, fluorescence).

3. Basic of Fusion 360. Virtual reality for Fusion model. 3D printing and segmentation (Slicer) in cardiology + practical 3D printing.

Individual preparation for laboratories

42 hours, optionally

Teacher / Lecturer

doc. Mgr. Zdenka Fohlerová, Ph.D.

Syllabus

Odborná příprava k tématu a nastudovaní materiálů k laboratorním cvičením.

Individual preparation for a final exam

20 hours, optionally

Teacher / Lecturer

doc. Mgr. Zdenka Fohlerová, Ph.D.