Detail publikačního výsledku

Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments

BURGETOVÁ, I.; ZENDULKA, J.; LEXA, M.

Original Title

Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments

English Title

Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments

Type

Paper in proceedings (conference paper)

Original Abstract

In this paper, we propose a novel method for clustering of protein substructures that we developed to study the relationships between protein sequences and their corresponding structures. We show the results of the comparison to other commonly used methods for clustering of protein structures. Finally, we outline a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.

English abstract

In this paper, we propose a novel method for clustering of protein substructures that we developed to study the relationships between protein sequences and their corresponding structures. We show the results of the comparison to other commonly used methods for clustering of protein structures. Finally, we outline a procedure for finding sequence profiles that tend to occur in more than one structural conformation but the number of their structural conformations is limited. This procedure is based on our method for protein substructure clustering.

Keywords

Clustering, density-based clustering, clustering of protein substructures, sequence-structure relationships in proteins

Key words in English

Clustering, density-based clustering, clustering of protein substructures, sequence-structure relationships in proteins

Authors

BURGETOVÁ, I.; ZENDULKA, J.; LEXA, M.

RIV year

2011

Released

01.09.2010

Publisher

Springer Verlag

Location

Heidelberg

ISBN

978-3-642-15019-7

Book

Information Technology in Bio- and Medical Informatics, ITBAM 2010

Edition

Lecture Notes in Computer Science

Volume

6266

Pages from

94

Pages to

101

Pages count

8

Full text in the Digital Library

http://hdl.handle.net/

BibTex

@inproceedings{BUT35834,
  author="Ivana {Burgetová} and Jaroslav {Zendulka} and Matej {Lexa}",
  title="Clustering of Protein Substructures for Discovery of a Novel Class of Sequence-Structure Fragments",
  booktitle="Information Technology in Bio- and Medical Informatics, ITBAM 2010",
  year="2010",
  series="Lecture Notes in Computer Science",
  volume="6266",
  pages="94--101",
  publisher="Springer Verlag",
  address="Heidelberg",
  doi="10.1007/978-3-642-15020-3\{_}9",
  isbn="978-3-642-15019-7"
}