The doctoral study provides the graduates of MSc study in the area of biomedical electronics and biocybernetics with a higher degree of education, deepening their theoretical background.
The study is aimed at deepening of theoretical knowledge of students in advanced mathematics, physics and in disciplins forming the theoretical basis of the chosen field. Also, necessary experience in experimental work and in processing of the obtained results should be provided, including exploitation of advanced methods of applied informatics.
The final goal is that the students will master methods of scientific research.

BOD> A graduate of the doctoral study is expected to be a distinct personality with a recognised research result, wide horizon of knowledge and ability to solve complex scientific and technical-research tasks in the field of biomedical electronics and biocybernetics and in neighbouring fields.
Maximum flexibility and professional adaptivity is the undisputed property of a graduate of doctoral study.
The graduates of the doctoral study in biomedical electronics and biocybernetics will be capable of working as scientists and researchers involved in basic or applied research namely in medical or biological area, as leading specialists in development and construction departments of research and development institutions, and in manufacturing enterprises or institutions exploiting advanced technology, namely in biomedical field.

Graduate of doctoral programme should be a strong personality with substantial scientific results, large horizon and ability to solve complex scientific and research technical tasks in area of biomedical electronics and biocybernetics. He/she will have maximum flexibility and professional adaptability in wide area of biomedical engineering. Graduates will be able to work as scientific and research staff in basic and applied research, as specialists in development, construction and production, in research institutes and at industrial companies and users of medical devices and applied information technologies in medicine and biology.

prof. Ing. Jiří Jan, CSc.

1. Analysis of high-frequency oscillations in electrocardiograms

   The main topics of the the study is development of signal processing methods of high-frequency multi leads ECG. Data measured with a high sampling frequency and dynamics will be used for processing. The frequency bandwidth will be at least 1.5kHz. 12-lead ECG will be measured at rest in a supine position and will include both healthy volunteers and patients with cardiac ischemia and heart transplant patients, a total of over 300 subjects. The aim of the study will be to design and implementation of methods for evaluating the characteristics of high frequency QRS complex in 12 lead ECG. The results will be put in perspective with additional markers and pathological findings and their diagnostic potential will be discussed. Doctoral student will actively participate in the realization of measurements, data organization and detection of basic parameters. Development of methods will be conducted mainly in Matlab software.

   Supervisor: Jurák Pavel, Ing., CSc.

2. Analysis of intra-QRS potentials in experimental cardiology

   The theme includes research of methods for analysis and evaluation of electrical activity of the heart muscle recorded in experiment. The experimental nature of the work allows to model pathologies on isolated animal hearts, especially local and global myocardial ischemia, and simultaneously record changes in the electrical activity of the heart. The aim of the project is to find and describe characteristic changes in the records that will enable early detection of acute ischemia due to reduced/stopped perfusion in coronary arteries. Found characteristic patterns will be compared to clinical tools for cardiovascular diseases. The project is financially supported by the project: GACR 102/11/1068 "Nano-electro-bio-tools for biochemical and molecular biological studies of eukaryotic cells (NanoBioTECell)".

   Supervisor: Provazník Valentýna, prof. Ing., Ph.D.

3. Measurements, analysis and relevance of ECG signal with high dynamic range

   The ECG measurement with high dynamic range allows acquiring ECG signal with frequency range up to 2 kHz. The amplitude of ECG signal intensely declines with increasing frequency and accessible frequency range is given by the properties of the acquisition system (dynamic range, noise figure), by the amount of electromagnetic noise in given environment and possibly by the influence of secondary biological signals caused by the excitation or intervention. Higher frequency components (100 Hz – 2 kHz) may contain the useful information and thus have a diagnostic and physiologic contribution. Verify the possibility of measurement and assessment of these components under the influence of heart excitations and maybe under some clinical interventions, their reproducibility and possible dependencies. Evaluate the diagnostic contribution of these components in comparison with generally used ECG (frequency band up to 100 Hz).

   Supervisor: Halámek Josef, Ing., CSc.

4. Monitoring of hemodynamic parameters using measurements by multichannel impedance monitor

   Deal with properties and parameters of the blood propagation in the extremities obtained by measuring multichannel electrical impedance. Focus on the analysis of changes in hemodynamic states, especially in relation of the pulse wave velocity and blood flow in monitored section. The aim of project will be evaluation of the contribution of bioimpedance measurements on multiple channels on the human body for the chosen method of evaluation of hemodynamic parameters.

   Supervisor: Vondra Vlastimil, Dr. Ing.