This bachelor's thesis explores the architectural, structural, and functional design of a detached single-family house located on Houškova street in Brno-Komín. The building is meticulously designed to respond to a challenging longitudinal slope, utilizing a dynamic split-level layout that organizes the home into a partially embedded ground floor, an open-plan social level, and a private first floor. A defining feature of the project is its innovative hybrid structural system. A reinforced concrete substructure provides crucial earth-retaining stability, while a Cross-Laminated Timber (CLT) superstructure acts as a self-supporting, cantilevered volume above. The interior celebrates this construction by leaving the timber elements exposed, complemented by premium wood-aluminum windows. Furthermore, the project is strictly engineered to meet the Nearly Zero-Energy Building (NZEB) standard, achieving an Energy Class A rating. This extreme efficiency is realized through a highly insulated thermal envelope, a vertical ground-source heat pump paired with underfloor heating, and roof-mounted photovoltaic panels. Ultimately, the thesis presents a comprehensive design solution that successfully balances structural innovation, environmental sustainability, and optimal user comfort.