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Master's Thesis
Author of thesis: Bc. Kamila Štumarová
Acad. year: 2025/2026
Supervisor: prof. Ing. Miloslav Pekař, CSc.
Reviewer: Ing. Andrea Hurčíková, Ph.D.
The aim of the master’s thesis is to prepare emulsion hydrogels from the ingredients accepted in natural cosmetics. Prepared emulgels should aid the healing of superficial wounds. Two concentrations of active substance were selected, specifically 1 and 5% for the preparation of emulsions. These emulsions were stabilized by three nonionic surfactants. Three different biopolymers were tested for the preparation of hydrogels, and one was subsequently selected as the most suitable in terms of ease of preparation and sensory properties. Flow characteristics of the prepared emulgels were studied using parallel plate rheometry. Stability of emulsion hydrogels was monitored using an analytical centrifuge at room and body temperature. The structure of emulgels was observed during storage using an optical microscope. Scratch test was used for the study of the effect of active substance on the wound closure. Based on the results, an optimal composition of the emulsion hydrogel was proposed.
emulsion hydrogels, emulgels, essential oil, nonionic surfactants, biopolymer, thermogravimetric analysis, differential scanning calorimetry, rheometry, analytical centrifuge, optical microscopy, scratch test, wound healing
Date of defence
21.05.2026
Date of publish
20.05.2029
Result of the defence
Defended (thesis was successfully defended)
Grading
A
Process of defence
Obhajoba proběhla podle následujícího schématu: prezentace studentky-vyjádření vedoucí/ho-oponentský posudek-reakce na posudek-diskuse s komisí. Studentka přednesla výborný výtah výsledků své diplomové práce, řádně zodpověděla všechny dotazy oponentské i členů komise, pohotově reagovala na připomínky. V diskusi tak studentka prokázala výbornou schopnost orientace v teoretických i praktických základech problematiky diplomové práce. Komise zhodnotila její diplomovou práci celkově jako výbornou. Obruča: Proč zrovna teatree oil? Jaká byla dávka média při scratch testu? Uvažovala jste i o jiném gelujícím materiálu než polysacharidech? Ješinová: Odkud byl teatree oil odebírán?
Language of thesis
Czech
Faculty
Fakulta chemická
Department
Institute of Physical and Applied Chemistry
Study programme
Chemistry for Medical Application (NPCP_CHMA)
Specialization
Processes and Materials of Medical Applications (BF)
Composition of Committee
doc. PharmDr. Ing. Radka Ješinová, Ph.D. (člen) doc. Ing. Zdenka Kozáková, Ph.D. (člen) prof. Ing. Stanislav Obruča, Ph.D. (místopředseda) prof. Ing. Miloslav Pekař, CSc. (předseda) doc. Ing. Petr Dzik, Ph.D. (člen)
Supervisor’s reportprof. Ing. Miloslav Pekař, CSc.
Grade proposed by supervisor: A
Reviewer’s reportIng. Andrea Hurčíková, Ph.D.
Grade proposed by reviewer: A
Reasons for publication postponement
Publication of the final thesis has been postponed in compliance with the provisions of Section 47b (4) of Act No. 111/1998 Coll., on the Higher Education Institutions and on amendments and supplements to other acts, as amended.
Protection of intellectual property
Responsibility: Mgr. et Mgr. Hana Odstrčilová