The diploma thesis is focused on the design and production of two innovative asphalt mixtures of the VMT 22 type into the base asphalt course. The newly produced blends contain modified binders, such as polymer modified bitumen (PMB) and Crumb rubber modified bitumen (CRMB). The theoretical part of the thesis describes the current state of the use of Reclaimed asphalt pavement in the base asphalt course. Furthermore, there are described types of asphalt mixtures for the base asphalt course are used in the Czech Republic and other countries. The conclusion of the theoretical part is devoted to the description of Reclaimed asphalt pavement (RAP), its storage and processing in a hot mix center. In the practical part of this thesis, there is described design and test of two High modulus asphalt mixture VMT 22, into which 25% RAP is dosed cold without rejuvenators. These asphalt mixtures are then subjected to functional tests (Stiffness of asphalt mixture test, Resistance to fatigue test, Low temperature properties of asphalt mixture test). The results of the functional tests are compared with the functional requirements in the Czech regulation TP 151. In the end of this thesis it is verified by means of the LayEps software that a suitable design of the asphalt mixture can significantly extend the road life.