Course detail

Bioengineering II

FCH-MC_BIO2Acad. year: 2023/2024

Bioengineering II is targeted to give students overview of industrial processing and production used in biochemical engineering, industrial microbiology, biotechnology and biomedical technologies. The students will understand the essential processess used in biochemical engineering processess such as measurement of dissolved oxygen, aeration, agitation, fermentation, cell growth in culture. They will understand that bioreactor is the main part of any biochemical proces for the production of biological products. The important part of the lectures are processess connected with upstream and downstream processing. At the end the lessons will explain the basic knowledge from tissue engineering and nanobiotechnology.

Language of instruction


Number of ECTS credits


Mode of study

Not applicable.

Entry knowledge

Without restriction

Rules for evaluation and completion of the course

During the semester and at the end of the semester, students take part on one written test focused on the calculations. The condition of the receiving credit (allowing for the exam) is to obtain 60% points. Students who do not meet this requirement may pass the test in two substitute terms in the exam period.

Exam will be in written form.The additional oral exam is possible if it is necessary.

Attendance at lectures is not obligatory but it is recommended. At seminars the calculations of model examples are given - attendance is obligatory.


The aim of this subject is to enable students to understand engineering principles related to biotechnology, chemical engineering and biomedical technologies used in bioengineering. The subject is focused on practical approaches used in bioengineering.
Students will understand the concept of bioengineering and the importance of basic operations associated with microorganisms and cell cultures cultivation. They will also be able to describe the importance of transport systems and tissue engineering from the point of view of bioengineering.

Study aids

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Kaštánek F.: Bioinženýrství, Academia, 2001 (CS)
Šebek J.: Buněčné kultury v medicíně, Galén, 2018. (CS)

Recommended reading

Not applicable.


Classification of course in study plans

  • Programme NPCP_PCHBT Master's, 1. year of study, winter semester, compulsory
  • Programme NKCP_CHPL Master's, 1. year of study, winter semester, compulsory
  • Programme NPCP_CHPL Master's, 1. year of study, winter semester, compulsory

  • Programme NPCP_CHMA Master's

    specialization CHBL , 2. year of study, winter semester, compulsory
    specialization BF , 2. year of study, winter semester, compulsory-optional

Type of course unit



26 hours, optionally

Teacher / Lecturer


1. Introduction, construction of bioreactors
2. Fundamental processes, parameters in submerged cultivations
3. Advanced cultivation processes and equipment
4. Immobilized systems
5. Membrane bioreactors
6. Cultivation of animal and plant cell cultures
7. Monitoring of the processes in bioreactors
8. Down-stream processes
9. Isolation and purification of proteins
10. Isolation of low-molecular metabolites
11. Advanced delivery systems in bioengineering
12. Tissue engineering
13. Nanobiotechnology

Guided consultation in combined form of studies

39 hours, optionally

Teacher / Lecturer


13 hours, compulsory

Teacher / Lecturer