Course detail
Biophysics
FEKT-MBFYAcad. year: 2012/2013
Interpretation of bioelectric phenomena. Electrical activity of living tissue on molecular, cellular and organ level. Methods of measurement of membrane voltage and membrane currents in isolated cells, recording of random pulse signals from membrane channels on molecular level. Origin and propagation of impulses of action voltage. Cellular basis of diagnostically significant electromagnetic field generated by organs. Coupling between electrical excitation and muscle contraction. Introduction to biomechanics. Mechanics of cardiovascular system. Introduction to biothermodynamics. Gibbs energy and electrochemical potentials in biophysics. Biophysics of ecosystem.
Language of instruction
Number of ECTS credits
Mode of study
Guarantor
Learning outcomes of the course unit
Prerequisites
Co-requisites
Planned learning activities and teaching methods
Assesment methods and criteria linked to learning outcomes
Course curriculum
Work placements
Aims
Specification of controlled education, way of implementation and compensation for absences
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Prerequisites and corequisites
Basic literature
J.Šimurda: Bioelektrické jevy I, CERM Brno, 1995 (CS)
Peusner L.: Základy bioenergetiky, Alfa Bratislava, 1984 (CS)
Recommended reading
Classification of course in study plans
Type of course unit
Lecture
Teacher / Lecturer
Syllabus
Physical interpretation of bioelectric phenomena, model, el. equivalent circuit.
Physical interpretation of action voltage origin and propagation. Quantitative description.
Methods of measurement and analysis of membrane voltage and membrane currents.
Bioelectrical signals on molecular level. Methods of measurement.
Membrane channels and carriers.
Excitable cell as a source of electromagnetic field.
Quantitative description of electromagnetic field generated by biological sources.
Biomechanics of muscle cell.
Mechanics of cardiovascular system.
Introduction to biothermodynamics.
Thermodynamics of bioelectrical phenomena.
Introduction to bioenergetics.
Laboratory exercise
Teacher / Lecturer
Syllabus
Measurement of excitability.
Cellular membrane as a dynamic system - computer simulations.
Preparation of experiment on isolated cells
Measurement of mechanical activity of cardiac cells.
Measurement and analysis of tissue impedance.