Course detail

Laboratory Classes in Special Toxicology

FCH-MCO_SPT_PAcad. year: 2011/2012

Practice of special toxicology contributes to widening of knowlidges in the field of special toxicology and make possible connection theoretical and practical knowledges and skills. Possibilities of practical determination of some toxic compounds in biotic and abiotic matrix, the detection some toxicological dates by experiment in laboratory conditions is the filling of practice. The explication of principles of toxicological exploration, problems of intoxication, possibilities of theoretical solving of choise case studies are other part of practice.

Language of instruction

Czech

Number of ECTS credits

4

Mode of study

Not applicable.

Guarantor

Mgr. Helena Doležalová Weissmannová, Ph.D.

Department

Institute of Chemistry and Technology of Environmental Protection (ÚCHTOŽP)

Learning outcomes of the course unit

The acquirement of new knowledges in the field of special toxicology and practical skills of determinations of toxic compounds.

Prerequisites

Basic knowledges of general toxicology, lectures of special toxicology and analytical chemistry.

Co-requisites

Not applicable.

Planned learning activities and teaching methods

Teaching methods depend on the type of course unit as specified in the article 7 of BUT Rules for Studies and Examinations.

Assesment methods and criteria linked to learning outcomes

Evaluation involves Elaborate a written paper of choise theme and presentation and desirable protocols from practical training.

Course curriculum

1. Introduction, safety in toxicological laboratory
2. Methods of sample preparing
3. Indetification of matals - Marsh test, Gutzeit test, Hg-test
4. Identification of alcaloids - sp. Nicotiana tabacum
5. Determination of warfarine
6. Aplication of TLC in drugs analysis
7. Aplication of TLC in Pahs identification, 2D-TLC
8. Screening identification of chlorine pesticides
9. Utilization of spectrophotometry in toxicological analysis. Chronic toxicity of metals.
10. Problems of intoxication, teoretical part - case studies.

Work placements

Not applicable.

Aims

The widening of knowledges in the field of special toxicology.
The acquirement of knowledges and skills during determination of some xenobiotics and natural toxins in environmental, specification of basic toxicologic dates.

Specification of controlled education, way of implementation and compensation for absences

The active participation is required, minimal attendance is 100%.
Eligible protocols from practical training.

Recommended optional programme components

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Not applicable.

Recommended reading

Fenton, J.J., Toxicology, A case-Oriented Approach, CRC Press LCC, Florida, 2002
Hrdina, V. a kol., Přírodní toxiny a jedy, Galén, Praha, 2004 (CS)

Classification of course in study plans

  • Programme NKCP_CHTOZP Master's

    branch NKCO_CHTOZP , 1. year of study, winter semester, compulsory

  • Programme NPCP_CHTOZP Master's

    branch NPCO_CHTOZP , 1. year of study, winter semester, compulsory

  • Programme CKCP_CZV lifelong learning

    branch CKCO_CZV , 1. year of study, winter semester, compulsory-optional

Type of course unit

 

Guided consultation in combined form of studies

26 hours, optionally

Teacher / Lecturer

Mgr. Helena Doležalová Weissmannová, Ph.D.

Laboratory exercise

26 hours, compulsory

Teacher / Lecturer

doc. MVDr. Helena Zlámalová Gargošová, Ph.D.