Publication detail

Identification of horizontal genes transfer elements across strains inhabiting the same niche using pan-genome analysis

SCHWARZEROVÁ, J. ČEJKOVÁ, D.

Original Title

Identification of horizontal genes transfer elements across strains inhabiting the same niche using pan-genome analysis

Type

conference paper

Language

English

Original Abstract

Tracing horizontal gene flux across strains in farm animals is one of the important steps for research focused on detection and genomic enzymology of genes conferring antibiotic resistance. In this study, we have built the comprehensive computational methodology for the detection of horizontal genes transfer elements via pan-genome analysis. In total, 133 anaerobes isolated from chicken gastrointestinal tract were examined for the presence of traits of horizontal transfer. The shared genes from all isolates, so called core genome genes were identified and characterised in order to assign the function to the gene within individual bacterial cell and within community of cells. This study provides an evidence that horizontal transmission frequently occurs not only between closely related bacteria, but also between distant taxonomical groups. Hence chickens are known primary reservoirs of antibiotic resistance genes, and the dissemination of these genes to other bacterial pathogens often leads to life-threatening infections, even within human population. Thus, the research on this subject, and the associated results are of a great importance for public health.

Keywords

Comparative Genomics, Core Genome, Antibiotics Resistance, Chicken Microbiome

Authors

SCHWARZEROVÁ, J.; ČEJKOVÁ, D.

Released

26. 4. 2022

Publisher

Brno University of Technology, Faculty of Electrical Engineering and Communication

Location

Brno

ISBN

978-80-214-6029-4

Book

Proceedings I of the 28th Conference STUDENT EEICT 2022 General Papers

Edition number

1

Pages from

416

Pages to

420

Pages count

5

URL

https://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2022_sbornik_1_v2.pdf

BibTex

@inproceedings{BUT179426,
  author="Jana {Schwarzerová} and Darina {Čejková}",
  title="Identification of horizontal genes transfer elements across strains inhabiting the same niche using pan-genome analysis",
  booktitle="Proceedings I of the 28th Conference STUDENT EEICT 2022 General Papers",
  year="2022",
  number="1",
  pages="416--420",
  publisher="Brno University of Technology, Faculty of Electrical Engineering and Communication",
  address="Brno",
  isbn="978-80-214-6029-4",
  url="https://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2022_sbornik_1_v2.pdf"
}