Detail publikačního výsledku

Identification of housekeeping genes in Clostridium beijerinckii NRRL B-598 RNA-Seq transcriptome

JUREČKOVÁ, K.; SEDLÁŘ, K.; PROVAZNÍK, I.

Original Title

Identification of housekeeping genes in Clostridium beijerinckii NRRL B-598 RNA-Seq transcriptome

English Title

Identification of housekeeping genes in Clostridium beijerinckii NRRL B-598 RNA-Seq transcriptome

Type

Paper in proceedings (conference paper)

Original Abstract

Housekeeping genes are responsible for maintenance of basic cellular function. Their expression level is expected to be constant under normal as well as stress conditions and in all stages of cell cycle. Thus, the housekeeping genes represent the minimal set of genes required to sustain life. In addition, the housekeeping genes are used in many biotechnological applications and genomic studies as reference genes for data normalization. In this study, we focused on identification of housekeeping genes in Clostridium beijerinckii NRRL B-598 genome. We performed bioinformatics analysis of transcriptomic data of this strain obtained by RNA-Seq technology and differential expression analysis of processed data revealed candidate reference genes for Clostridium beijerinckii NRRL B-598.

English abstract

Housekeeping genes are responsible for maintenance of basic cellular function. Their expression level is expected to be constant under normal as well as stress conditions and in all stages of cell cycle. Thus, the housekeeping genes represent the minimal set of genes required to sustain life. In addition, the housekeeping genes are used in many biotechnological applications and genomic studies as reference genes for data normalization. In this study, we focused on identification of housekeeping genes in Clostridium beijerinckii NRRL B-598 genome. We performed bioinformatics analysis of transcriptomic data of this strain obtained by RNA-Seq technology and differential expression analysis of processed data revealed candidate reference genes for Clostridium beijerinckii NRRL B-598.

Keywords

housekeeping genes; RNA-Seq

Key words in English

housekeeping genes; RNA-Seq

Authors

JUREČKOVÁ, K.; SEDLÁŘ, K.; PROVAZNÍK, I.

RIV year

2020

Released

29.10.2019

Publisher

Czech Society of Industrial Chemistry

ISBN

978-80-88307-00-6

Book

Proceedings of the 7th International Conference on Chemical Technology

Pages from

67

Pages to

71

Pages count

5

URL

https://www.medsci.cn/sci/show_paper.asp?id=f4c3a121a852869f

Full text in the Digital Library

http://hdl.handle.net/

BibTex

@inproceedings{BUT159557,
  author="Kateřina {Šabatová} and Karel {Sedlář} and Valentýna {Provazník}",
  title="Identification of housekeeping genes in Clostridium beijerinckii NRRL B-598 RNA-Seq transcriptome",
  booktitle="Proceedings of the 7th International Conference on Chemical Technology",
  year="2019",
  pages="67--71",
  publisher="Czech Society of Industrial Chemistry",
  isbn="978-80-88307-00-6",
  url="https://www.medsci.cn/sci/show_paper.asp?id=f4c3a121a852869f"
}